UTSA COS Summer Research Experience for 2013
Dr. Chiung-Yu Hung
Mechanisms of Fungal Virulence and Vaccine Development Against Fungal Infections
A major focus of our research is to study host-fungal pathogen interactions utilizing multidisciplinary approaches including bioinformatics, molecular biology, genetic methodologies, microbiology, cellular biology, and immunological techniques. Studies of the interaction may lead to a better understanding of fungal infections, and to the identification of vaccine candidates or novel therapeutic drug targets. Specifically, our studies are directed to develop an antifungal vaccine and drug targets which can be translated to clinical application. Students will be trained to involve in research related to identification of fungal T cell antigens and immunoreactive compounds, which elicit innate immunity or stimulate acquired immunity to fungal infections. We are also interested in creation and production of recombinant fungal antigens and characterization of experimental adjuvants which can enhance vaccine-induced immunity.