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COURSE DESCRIPTIONS CHEMISTRY (CHE)

5263 Advanced Analytical Chemistry
(3-0)3 hours credit. Prerequisites: CHE 3224 and CHE 4253, or equivalents. The physical and chemical principles of modern instrumental techniques used for chemical analysis, with emphasis on absorption, emission, magnetic resonance, and Raman spectroscopies; mass spectrometry; chromatography; electrophoresis; and electrochemical techniques. (Formerly CHE 5163. Credit cannot be earned for both CHE 5263 and CHE 5163.)

5313 Advanced Biochemistry
(3-0)3 hours credit. Prerequisite: Undergraduate biochemistry. Theory and application of physical chemistry to biological macromolecular systems of interest including such topics as reaction kinetics, protein folding and denaturation, ligand interactions, and the thermodynamics and mechanisms underlying how these important macromolecules interact with each other as well as spectroscopic determination of nucleic acid and protein structures, and reactions using techniques such as nuclear magnetic resonance spectroscopy, mass spectrometry and x-ray diffraction.

5453 Advanced Inorganic Chemistry
(3-0)3 hours credit. Prerequisite: CHE 4263 or an equivalent. Modern theories of chemical bonding, structure of inorganic compounds, reaction mechanisms, cluster compounds, organometallic chemistry, and bioinorganic chemistry. (Formerly CHE 5133. Credit cannot be earned for both CHE 5453 and CHE 5133.)

5643 Advanced Organic Chemistry
(3-0)3 hours credit. Prerequisites: 8 semester credit hours each of undergraduate organic chemistry and physical chemistry or graduate standing in chemistry. An advanced study of topics in organic chemistry such as stereochemistry, conformational analysis, nonbenzenoid, aromaticity, molecular orbital theory, and organic reaction mechanisms. Applications of these concepts to the structure and reactivity of biomolecules such as peptides and proteins, nucleic acids, and carbohydrates. (Formerly CHE 5113. Credit cannot be earned for both CHE 5643 and CHE 5113.)

5843 Advanced Physical Chemistry
(3-0)3 hours credit. Prerequisite: Graduate student advisor consent. An advanced study of group theory, and its application to molecular orbital theory, electronic/vibrational/rotational spectroscopy, and chemical reactivity.

5912 Introduction to Chemical Research
(0-6) 2 hours credit. Prerequisite: Graduate standing in chemistry. Participation in various research laboratories (3-lab rotation) throughout the semester to become familiar with the ways research is formulated and carried out. One month will be spent in each of three different laboratories attending all group meetings and research colloquia associated with the research group. The grade report for the course is either “CR” (satisfactory performance) or “NC” (unsatisfactory performance) and will be based on attendance.

5923 Teaching and Research Practice and Ethics
(3-0)3 hours credit. Prerequisites: Graduate standing in chemistry and concurrent designation as a teaching assistant in the chemistry program or consent of instructor. The course is designed to improve the instructional effectiveness of graduate students teaching at the college level. The course will cover, but is not limited to, board-work, clear speech, teacher-student interaction, professional responsibilities, course content and pace, grading policy, quiz writing, sensitivity training to student needs, information on technical support, and guest lecturers on special topics. Research ethics will be discussed based on case studies. The grade report for the course is either “CR” (satisfactory performance) or “NC” (unsatisfactory performance).

5981 Graduate Seminar in Chemistry
(0-3) 1 hour credit. Prerequisite: Graduate standing in chemistry or consent of the Graduate Advisor of Record. Current research and literature seminars presented by faculty, visiting lecturers, and doctoral candidates. Students in the Doctoral chemistry program must register every semester while in residence, but only 8 hours will apply toward the Doctoral degree.

6603 Introduction to Polymer Chemistry
(3-0)3 hours credit. Prerequisite: Consent of instructor. Fundamental concepts of polymer chemistry, including mechanisms for synthesis, kinetics, and copolymerization; molecular weight, stereoisomerism, morphology, solubility, and thermal transitions; viso- and rubber elasticity; and the molecular basis for physical properties.

6863 NMR Spectroscopy
(3-0)3 hours credit. Prerequisite: Consent of instructor. A lecture course with demonstrations dealing with the basic theory and applications of one-and two-dimensional nuclear magnetic resonance spectroscopy, including the interpretation of spectra. The parameters and the pulse sequences for various types of NMR experiments and explanations of how molecular structural information can be obtained will be presented.

6883 Mass Spectrometry
(2-3) 3 hours credit. Prerequisite: Consent of instructor. The basic principles of interpreting mass spectra and how they are produced. The effect the method of ion production has on the observed mass spectra, and the theory and operation of various types of mass spectrometers will be covered. The basic theory of ion-molecule reactions and other advanced topics will be presented.

6903 Progress in Chemistry - Master’s
(3-0)3 hours credit. Prerequisite: Consent of instructor. An organized course offering the opportunity for a specialized study of current aspects of chemistry not normally available as part of the regular course offerings. The course may be repeated for credit, but not more than 6 hours may be applied to the Master’s degree.

6951-3 Independent Study
1 to 3 hours credit. Prerequisites: Graduate standing and permission in writing (form available) of the instructor and the student’s Graduate Advisor of Record. Independent reading, research, discussion, and/or writing under the direction of a faculty member. May be repeated for credit, but not more than 6 hours, regardless of discipline, will apply to the Master’s degree.

6961 Comprehensive Examination
1 hour credit. Prerequisite: Approval of the appropriate Graduate Program Committee. Independent study course for the purpose of taking the Comprehensive Examination. May be repeated as many times as approved by the Graduate Program Committee. Enrollment is required each term in which the Comprehensive Examination is taken if no other courses are being taken that term. The grade report for the course is either “CR” (satisfactory performance on the Comprehensive Examination) or “NC” (unsatisfactory performance on the Comprehensive Examination).

6973 Special Problems
(3-0)3 hours credit. Prerequisite: Consent of instructor. An organized course offering the opportunity for specialized study not normally or not often available as part of the regular course offerings. Special Problems courses may be repeated for credit when the topics vary, but not more than 6 hours, regardless of discipline, will apply to the Master’s degree.

6983 Master’s Thesis
3 hours credit. Prerequisite: Permission of the Graduate Advisor of Record and thesis director. Thesis research and preparation. May be repeated for credit, but not more than 6 hours will apply to the Master’s degree. Credit will be awarded upon completion of the thesis. Enrollment is required each term in which the thesis is in progress.

6991-3 Directed Research
1 to 3 hours credit. Prerequisites: Graduate standing and permission in writing (form available) of the instructor and the student’s Graduate Advisor of Record. The directed research course may involve either a laboratory or a theoretical problem. Normally a written report is required. May be repeated for credit, but not more than 6 hours or 18 hours, regardless of discipline, will apply to the Master’s degree or Doctoral degree, respectively. (Formerly CHE 5973.)

7263 Recent Advances in Bioanalytical Chemistry
(3-0)3 hours credit. Prerequisite: Consent of instructor and Graduate Advisor of Record. A survey of modern analytical techniques used in studies of biological interest from both theoretical and practical perspectives.

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7403 Bioinorganic Chemistry
(3-0)3 hours credit. Prerequisite: CHE 5453 or consent of instructor. Study of the functions, reaction sites, mechanisms, molecular architecture, and medicinal aspects of metal ions in biological systems including bioorganometallic compounds. A discussion of the experimental techniques will be included.

7433 Organometallic Chemistry
(3-0)3 hours credit. Prerequisite: CHE 5453 or consent of instructor. Preparation, bonding and reactivity of organometallic compounds, both main group and transition metals.

7603 Bioorganic Chemistry
(3-0)3 hours credit. Prerequisite: CHE 5643 or consent of instructor. Chemical transformations of biologically important organic compounds; examination of enzyme active sites. Discussion of theories of catalysis, stereochemistry, electron-transfer, and molecular structure in the context of biological systems. (Formerly CHE 5503. Credit cannot be earned for both CHE 7603 and CHE 5503.)

7623 Methods of Organic Synthesis
(3-0)3 hours credit. Prerequisite: CHE 5643 or consent of instructor. A study of modern methods of organic functional group transformation, simple carbon skeleton construction, asymmetric synthesis, introduction to the synthon concept and to retrosynthetic analytical methodology for designing rational synthetic approaches to complex organic molecules of biological interest. (Formerly CHE 6123. Credit cannot be earned for both CHE 7623 and CHE 6123.)

7673 Advanced Topics in Medicinal Chemistry
(3-0)3 hours credit. Prerequisite: Consent of instructor and Graduate Advisor of Record. Approaches to drug design and development; a rational target-oriented approach and a combinatorial approach. Mechanisms of drug action on enzymes, receptors, and nucleic acids. Strategies for the preparation of series of analogs for the structure-activity investigations.

7683 Topics in the Chemistry of Natural Products
(3-0)3 hours credit. Prerequisites: CHE 5643 and CHE 7623. Selected topics in the chemistry and biochemistry of natural products and related compounds of biological and medicinal interest. Course may be repeated for credit when topics vary, but not more than 6 hours may apply to the doctoral degree. (Formerly CHE 6183. Credit cannot be earned for both CHE 7683 and CHE 6183.)

7813 Molecular Thermodynamics
(3-0)3 hours credit. Prerequisite: Consent of Graduate student advisor. A molecular approach to the study of the physiochemical properties of gases, liquids, and solids. (Formerly CHE 5213. Credit cannot be earned for both CHE 7813 and CHE 5213.)

7823 Chemical Kinetics and Dynamics
(3-0)3 hours credit. Prerequisite: Consent of Graduate student advisor. An advanced study of topics in chemical kinetics and dynamics. (Formerly CHE 5223. Credit cannot be earned for both CHE 7823 and CHE 5223.)

7833 Quantum Chemistry
(3-0)3 hours credit. Prerequisite: Consent of Graduate student advisor. The application of quantum mechanical methods to many-body chemical systems. (Formerly CHE 5243. Credit cannot be earned for both CHE 7833 and CHE 5243.)

7843 Computational Chemistry
(3-0)3 hours credit. Prerequisite: Graduate student status. The application of molecular mechanical, molecular orbital, and density functional methods to problems of molecular structure, property, reactivity, and spectroscopy.

7853 Biophysical Chemistry
(3-0)3 hours credit. Prerequisite: Graduate student status. The study of the structure/function relations of proteins, nucleic acids, membranes, and other macromolecular biomolecules using spectroscopic methods. (Formerly CHE 5513. Credit cannot be earned for both CHE 7853 and CHE 5513.)

7903 Progress in Chemistry - Doctoral
(3-0)3 hours credit. Prerequisite: Consent of instructor. An organized course offering the opportunity for a specialized study of current aspects of chemistry not normally available as part of the regular course offerings. The course may be repeated for credit, but not more than 6 hours may be applied to the Doctoral degree.

7911 Chemistry Research Colloquium
(1-0) 1 hour credit. Prerequisite: Graduate standing in chemistry. Discussions of current journal articles, reviews, and recent advances in specialized areas of chemistry (including current research progress of students). May be repeated for credit as topics vary. The grade report for this course is either “CR” (satisfactory participation in the colloquium) or “NC” (unsatisfactory participation in the colloquium).

7921-3 Doctoral Research
1 to 3 hours credit. Prerequisite: Graduate standing in chemistry. Doctoral research and preparation. May be repeated for credit, but not more than 18 hours will apply to the doctoral degree. Enrollment in either CHE 7921-3 or CHE 7931-3, depending on progress, is required each term in which the dissertation is in progress.

7931-3 Doctoral Dissertation
1 to 3 hours credit. Prerequisite: Permission of the Graduate Advisor of Record and dissertation director. Preparation and writing of the Doctoral dissertation. May be repeated for credit, but not more than 12 hours will apply to the Doctoral degree. Enrollment in either CHE 7921-3 or CHE 7931-3, depending on progress, is required each term in which the dissertation is in progress.

7973 Special Problems
(3-0)3 hours credit. Prerequisite: Consent of instructor. An organized course offering the opportunity for specialized study not normally or not often available as part of the regular course offerings. Special Problems courses may be repeated for credit when the topics vary, but not more than 6 hours, regardless of discipline, will apply to the doctoral degree.

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