(Dec. 15, 2009)--Led by Joe L. Martinez Jr., UTSA Ewing Halsell Distinguished Chair in Biology, a team of UTSA researchers found that radiation therapy can prevent the brain from forming some types of fearful memories. Further research may lead to treatments for post-traumatic stress disorder and Alzheimer's disease.
Radiation therapy reduces the number of new granule cells in the hippocampus, the part of the brain responsible for autobiographical memory. Cranial irradiation, or radiation of the skull, is commonly used as a treatment to prevent cancer from spreading to the brain. However, long-term cognitive impairments, such as the inability to learn or remember new tasks, often occur as a result of the procedure.
The researchers tested the ability of rats to form three types of fear memories: delay fear memories, context fear memories and trace fear memories. Delay fear memories form when a fearful situation occurs simultaneously with another event. Context fear memories form when a fearful situation follows another event and both take place in the same physical space. Trace fear memories form when an event and a fearful situation are separated by a pause.
Combining biological and psychological approaches in the laboratory, the researchers observed the behavior of rats not producing new granule cells in their brains. The researchers observed that the rats were able to form delay and fear memories but were unable to form trace fear memories. The findings led them to believe that new granule cells are not required in the hippocampus of the brain to form delay and context fear memories but are required for the formation of trace fear memories.
"This research has broad applications including treatments for post-traumatic stress disorder and Alzheimer's disease," said Martinez. "If we can pinpoint the neurons in the hippocampus that are responsible for storing trace fear memories, we may be able to selectively erase negative memories by decreasing the number of new granule cells in the brain. Or, we may be able to prevent memory loss by preventing the death of new granule cells. Such therapies could definitely enhance an individual's life, but we have a long way to go before we put the theory into practice."
Langston Clark, UTSA assistant professor in the Department of Kinesiology, Health, and Nutrition will discuss exploring the historical context for the role of black athletes in contemporary social movements.
John Peace Library, Assembly Room (JPL 4.04.22), Main Campus
The UTSA African American Studies program invites speakers from the leading African American Fraternities and Sororities for a panel discussion of the history of each organization and to enlighten the audience about the community service, academic purpose, professionalism and ethical roots of each group.
Student Union, Mesquite Room (SU 2.01.24), Main Campus
MuTe Fest is a celebration of original music and technology. Three days of concerts, sessions, and informative lectures will offer a unique experience of musical works created by fellow UTSA students and the chance to gain valuable knowledge about music technology.
Art Building, Music Tech Lab (Arts 3.01.30B), Main Campus
UTSA Libraries hosts Assistant Professor Ian Caine for his lecture, Architectural Postcards from Space, as part of the popular Pizza + Research series. Pizza will be served while supplies last.
Buena Vista Street Building (BVB 2.304), Downtown Campus
The theme of this year’s symposium is Black & Brown Futures. The free event will give UTSA students and the community the opportunity to meet and hear national scholars talk about current research and academic trends relevant to the lives of African Americans in the United States.
Student Union, Denman Room (SU 2.01.28), Main Campus
Registration is open now for this family-friendly and dog-friendly run that supports the UTSA Alumni Association scholarship fund.
Convocation Center, Main Campus
Join the Department of Interdisciplinary Learning and Teaching for the 14th Annual UTSA Storytelling Festival featuring Nancy Simpson, storyteller and keynote speaker. The event is free and open to the public.
Main Building, Ground Floor Lobby, Main Campus
Students are invited to a semi-formal, dinner banquet with an awards presentation and dancing. Keynote speaker will be San Antonio City Councilman William Cruz Shaw. Tickets must be purchased by Feb 19 at Roadrunner Express. UTSA students are $15 and guests are $20.
H-E-B Student Union Ballroom (HSU 1.104/1/106), Main Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
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