(Dec. 15, 2009)--Led by Joe L. Martinez Jr., UTSA Ewing Halsell Distinguished Chair in Biology, a team of UTSA researchers found that radiation therapy can prevent the brain from forming some types of fearful memories. Further research may lead to treatments for post-traumatic stress disorder and Alzheimer's disease.
Radiation therapy reduces the number of new granule cells in the hippocampus, the part of the brain responsible for autobiographical memory. Cranial irradiation, or radiation of the skull, is commonly used as a treatment to prevent cancer from spreading to the brain. However, long-term cognitive impairments, such as the inability to learn or remember new tasks, often occur as a result of the procedure.
The researchers tested the ability of rats to form three types of fear memories: delay fear memories, context fear memories and trace fear memories. Delay fear memories form when a fearful situation occurs simultaneously with another event. Context fear memories form when a fearful situation follows another event and both take place in the same physical space. Trace fear memories form when an event and a fearful situation are separated by a pause.
Combining biological and psychological approaches in the laboratory, the researchers observed the behavior of rats not producing new granule cells in their brains. The researchers observed that the rats were able to form delay and fear memories but were unable to form trace fear memories. The findings led them to believe that new granule cells are not required in the hippocampus of the brain to form delay and context fear memories but are required for the formation of trace fear memories.
"This research has broad applications including treatments for post-traumatic stress disorder and Alzheimer's disease," said Martinez. "If we can pinpoint the neurons in the hippocampus that are responsible for storing trace fear memories, we may be able to selectively erase negative memories by decreasing the number of new granule cells in the brain. Or, we may be able to prevent memory loss by preventing the death of new granule cells. Such therapies could definitely enhance an individual's life, but we have a long way to go before we put the theory into practice."
Join the Center for Military Families for a panel on Politics in the Service of Military Families, featuring Cedric Leighton, David Splitter, Steve Huerta, and the Office of Congressman Henry Cuellar. The event is free and open to the public.
Buena Vista Street Building, Aula Canaria Lecture Hall (BVB 1.328), Downtown Campus
UTSA Dance classes will take the stage and share their talents and passion for dance! Come support our growing dance program! $10 admission
Buena Vista Street Building Theater (BVB 1.326), Downtown Campus
This panel presentation will look at the history of the YWCA and the impact the organization has had on women in the San Antonio community.
McKinney Humanities Building (MH 2.02.10), Main Campus
The Demography Lecture Series continues with Dr. Barbara Bird of American University. Her topic focuses on Insights Into a Hard to Find Population: Latino Entrepreneurs in Metro Washington, D.C. Event is free and open to the public. Parking is available in the pay stall spaces of the Monterrey surface lot.
Monterrey Building (MNT 3.240), Downtown Campus
This video tells the story of four Latina lesbians who fought for exoneration after being wrongfully convicted of sexually assaulting two girls during the Satanic Panic witch-hunt era of the 1980s and 1990s.
H-E-B University Center, Bexar Room (HUC 1.102), Main Campus
Tejana/Indígena author Ire'ne Lara Ailva will read from her latest work and discuss her approach to reimagining Tejan@ myths.
Main Building (MB 2.404), Main Campus
Muralist Crystal Arias will discuss her current mural "Cultivate the Past to Prestige" at La India Herbs and themes she utilizes in her other works.
McKinney Humanities Building (MH 3.02.26), Main Campus
The UTSA Department of Modern Languages and Literatures is a co-sponsor of the CARTA 19th Annual Conference. The group meets annually to exchange educational programs, ideas, and techniques and to network with other teachers of Russian. Registration required.
DoubleTree by Hilton, Downtown San Antonio
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