(Dec. 15, 2009)--Led by Joe L. Martinez Jr., UTSA Ewing Halsell Distinguished Chair in Biology, a team of UTSA researchers found that radiation therapy can prevent the brain from forming some types of fearful memories. Further research may lead to treatments for post-traumatic stress disorder and Alzheimer's disease.
Radiation therapy reduces the number of new granule cells in the hippocampus, the part of the brain responsible for autobiographical memory. Cranial irradiation, or radiation of the skull, is commonly used as a treatment to prevent cancer from spreading to the brain. However, long-term cognitive impairments, such as the inability to learn or remember new tasks, often occur as a result of the procedure.
The researchers tested the ability of rats to form three types of fear memories: delay fear memories, context fear memories and trace fear memories. Delay fear memories form when a fearful situation occurs simultaneously with another event. Context fear memories form when a fearful situation follows another event and both take place in the same physical space. Trace fear memories form when an event and a fearful situation are separated by a pause.
Combining biological and psychological approaches in the laboratory, the researchers observed the behavior of rats not producing new granule cells in their brains. The researchers observed that the rats were able to form delay and fear memories but were unable to form trace fear memories. The findings led them to believe that new granule cells are not required in the hippocampus of the brain to form delay and context fear memories but are required for the formation of trace fear memories.
"This research has broad applications including treatments for post-traumatic stress disorder and Alzheimer's disease," said Martinez. "If we can pinpoint the neurons in the hippocampus that are responsible for storing trace fear memories, we may be able to selectively erase negative memories by decreasing the number of new granule cells in the brain. Or, we may be able to prevent memory loss by preventing the death of new granule cells. Such therapies could definitely enhance an individual's life, but we have a long way to go before we put the theory into practice."
The Office of International Programs will host a Study Abroad Fair for students interested in taking their academics abroad.
University Center main corridor, Main Campus
The UTSA Institute for P-20 Initiatives and the Texas Mentoring Partnership hosts the 5th Annual Texas Mentoring Summit. The theme Mentoring: A Pathway To and Through College & Career will focus on the positive impact mentoring can have on student success from k-12 through college and beyond.
Wyndham Riverwalk Hotel, Downtown San Antonio
The UTSA Department of Physics and Astronomy invites everyone to its monthly lecture and stargazing at the Curtis Vaughan Jr. Observatory.
Flawn Science Building (FLN 2.02.02), Main Campus
The UTSA Music Department presents Miller-Porfiris Duo (violin/viola) in a performance of period appropriate music as accompaniment to the silent films, "The Great Train Robbery," "The Violinmaker of Cremona," and "Ballet Mecanique."
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The CACP 2016-2017 Speaker Series continues with architect and writer Jason Griffiths of the University of Arizona and Jason Griffiths Architecture. His practice is based on a multidisciplinary approach.
Buena Vista Building, Aula Canaria Auditorium (BVB 1.328), Downtown Campus
UTSA's Department of Music hosts Dr. David Huron from Ohio State University as part of the Donald Hodges lecture series. Huron is a Canadian arts and humanities distinguished professor at Ohio State University.
John Peace Library, UTSA Faculty Center, (JPL 4.04.22), Main Campus
The UTSA community is encouraged to donate blood and save a life. Donors will also receive a free t-shirt.
H-E-B University Center parking lot, Main Campus
Dr. Stephanie Westney (violin) presents a concert of Mozart compositions as performed by herself and other talented musicians from the university and surrounding area. This concert is free and open to the public.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The Student Center for Community Engagement and Inclusion annually hosts a Volunteer Opportunities Fair to allow students, faculty and staff to learn about volunteer and service-learning opportunities in the San Antonio area.
University Center, 1st floor corridor, Main Campus
Join the conversation about the experiences of military-connected families in transition. Free parking in the Cattleman Square (along Buena Vista Street). The event is free and open to the public.
Frio Street Building, Riklin Auditorium (FS 1.406), Downtown Campus
School district superintendents and other district leaders responsible for bilingual and ESL programs' administration and accountability learn about cultural literacy, language, and diversity in the community.
Recruiters from across the STEM fields will be present with full-time, part-time and/or internship opportunities. Dress professional and bring plenty of resumes.
Convocation Center, Main Campus
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