(July 1, 2010) Doug E. Frantz, UTSA assistant professor of chemistry in the College of Sciences, has received the Max and Minnie Tomerlin Voelcker Fund 2010 Young Investigator Award, which includes $450,000 over the next three years to propel Frantz's medicinal chemistry research program. This is the first time a UTSA researcher will be honored with the award, which recognizes and supports promising medical research that has the potential to have a significant impact on patient care.
"By supporting research in its own backyard, the Voelcker Fund is providing a great opportunity to San Antonio medical researchers and particularly UTSA," said UTSA President Ricardo Romo. "With the outstanding support and leadership of community partners like the Voelcker Fund, UTSA will achieve premier research university status at a much faster pace."
In 2009, the Voelcker Fund began to present the award annually to assistant professors making significant research contributions that advance clinical treatment in five key areas. The target areas include heart disease, cancer, arthritis, muscular dystrophy and maculative degeneration of the retina.
"The purpose of the Voelcker Fund is to elevate research to cure targeted diseases. We are impressed with the level and focus of the scientific research being conducted by Dr. Frantz," said Voelcker Fund trustee Banks M. Smith.
Over the long term, Frantz and collaborators Jay Schneider and Jenny Hsieh of the University of Texas Southwestern Medical Center at Dallas will discover, synthesize and test libraries of small drug-like molecules that target stem cells with the potential to treat heart disease and brain cancer. In the area of heart disease, Frantz is working to identify molecules that will nudge adult stem cells to grow into new heart muscle cells instead of generating scar tissue after a heart attack.
In brain cancer, his research involves the discovery of new molecules that will turn cancerous stem cells into normal benign neurons. Currently, the researchers are targeting two classes of molecules, isoxazoles and pyrazoles, which have demonstrated success in inducing stem cells to become heart cells and neurons and have been published for the scientific community to review.
The research we are conducting in the laboratory is perfectly aligned with the broader issues of treating cardiovascular disease and cancer by combining stem cells and medicinal chemistry, said Frantz. I am extremely grateful to the trustees of the Voelcker Fund for recognizing the potential of this research and generously supporting my laboratory's research program. In addition to advancing our research, the funds support will provide undergraduates and graduate students with the opportunity to gain valuable laboratory experience at the interface of chemistry and biology and contribute to the development of therapeutic solutions for a variety of diseases.
Frantz joined UTSA in 2009 from UT Southwestern Medical Center, where he was an assistant research professor and served as director of the medical center's synthetic chemistry core facility from 2005 to 2009. At the medical center, he focused on the development of new methods in organic synthesis, medicinal chemistry, physical organic chemistry and the synthesis of natural products.
From 2000 to 2005, Frantz worked in industry for pharmaceutical corporation Merck and Co. Inc. initially as a senior research scientist and then as a research fellow in the corporation's Department of Process Research. While at Merck, Frantz managed a group of process chemists in developing pre-clinical and clinical drug candidates for eventual manufacturing and distribution. He also consulted for Reata Pharmaceuticals based in Los Colinas, Texas, and Joyant Pharmaceuticals based in Dallas.
The CACP 2016-2017 Speaker Series continues with architect and writer Jason Griffiths of the University of Arizona and Jason Griffiths Architecture. His practice is based on a multidisciplinary approach.
Buena Vista Building, Aula Canaria Auditorium (BVB 1.328), Downtown Campus
UTSA's Department of Music hosts Dr. David Huron from Ohio State University as part of the Donald Hodges lecture series. Huron is a Canadian arts and humanities distinguished professor at Ohio State University.
John Peace Library, UTSA Faculty Center, (JPL 4.04.22), Main Campus
The UTSA community is encouraged to donate blood and save a life. Donors will also receive a free t-shirt.
H-E-B University Center parking lot, Main Campus
Dr. Stephanie Westney (violin) presents a concert of Mozart compositions as performed by herself and other talented musicians from the university and surrounding area. This concert is free and open to the public.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The Student Center for Community Engagement and Inclusion annually hosts a Volunteer Opportunities Fair to allow students, faculty and staff to learn about volunteer and service-learning opportunities in the San Antonio area.
University Center, 1st floor corridor, Main Campus
Join the conversation about the experiences of military-connected families in transition. Free parking in the Cattleman Square (along Buena Vista Street). The event is free and open to the public.
Frio Street Building, Riklin Auditorium (FS 1.406), Downtown Campus
School district superintendents and other district leaders responsible for bilingual and ESL programs' administration and accountability learn about cultural literacy, language, and diversity in the community.
Recruiters from across the STEM fields will be present with full-time, part-time and/or internship opportunities. Dress professional and bring plenty of resumes.
Convocation Center, Main Campus
Recruiters from across all fields looking to hire students with all different majors will be present at this event looking to hire for their full-time and/or internship opportunities. Professional dress is required. Bring plenty of resumes.
Convocation Center, Main Campus
The Civic Engagement Summit is an opportunity to celebrate and showcase UTSA's commitment to civic engagement through a myriad of efforts by students, faculty and staff, highlighting the significant ways the university impacts the local community.
H-E-B University Center Ballroom, (HUC 1.104), Main Campus
The Department of Demography presents Dr. Rodolfo Cruz Peñeiro of El Colegio de la Frontera Norte. His presentation is titled "Changes in the Migratory Dynamics of the Northern Mexican Border." This event is free and open to the public.
Monterrey Bldg., (MNT 3.240), UTSA Downtown Campus
Grab your friends, family, kids and dog for this annual fun run on the UTSA Main Campus benefititng the UTSA Alumni Association.
Convocation Center, Main Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
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