(July 1, 2010) Doug E. Frantz, UTSA assistant professor of chemistry in the College of Sciences, has received the Max and Minnie Tomerlin Voelcker Fund 2010 Young Investigator Award, which includes $450,000 over the next three years to propel Frantz's medicinal chemistry research program. This is the first time a UTSA researcher will be honored with the award, which recognizes and supports promising medical research that has the potential to have a significant impact on patient care.
"By supporting research in its own backyard, the Voelcker Fund is providing a great opportunity to San Antonio medical researchers and particularly UTSA," said UTSA President Ricardo Romo. "With the outstanding support and leadership of community partners like the Voelcker Fund, UTSA will achieve premier research university status at a much faster pace."
In 2009, the Voelcker Fund began to present the award annually to assistant professors making significant research contributions that advance clinical treatment in five key areas. The target areas include heart disease, cancer, arthritis, muscular dystrophy and maculative degeneration of the retina.
"The purpose of the Voelcker Fund is to elevate research to cure targeted diseases. We are impressed with the level and focus of the scientific research being conducted by Dr. Frantz," said Voelcker Fund trustee Banks M. Smith.
Over the long term, Frantz and collaborators Jay Schneider and Jenny Hsieh of the University of Texas Southwestern Medical Center at Dallas will discover, synthesize and test libraries of small drug-like molecules that target stem cells with the potential to treat heart disease and brain cancer. In the area of heart disease, Frantz is working to identify molecules that will nudge adult stem cells to grow into new heart muscle cells instead of generating scar tissue after a heart attack.
In brain cancer, his research involves the discovery of new molecules that will turn cancerous stem cells into normal benign neurons. Currently, the researchers are targeting two classes of molecules, isoxazoles and pyrazoles, which have demonstrated success in inducing stem cells to become heart cells and neurons and have been published for the scientific community to review.
The research we are conducting in the laboratory is perfectly aligned with the broader issues of treating cardiovascular disease and cancer by combining stem cells and medicinal chemistry, said Frantz. I am extremely grateful to the trustees of the Voelcker Fund for recognizing the potential of this research and generously supporting my laboratory's research program. In addition to advancing our research, the funds support will provide undergraduates and graduate students with the opportunity to gain valuable laboratory experience at the interface of chemistry and biology and contribute to the development of therapeutic solutions for a variety of diseases.
Frantz joined UTSA in 2009 from UT Southwestern Medical Center, where he was an assistant research professor and served as director of the medical center's synthetic chemistry core facility from 2005 to 2009. At the medical center, he focused on the development of new methods in organic synthesis, medicinal chemistry, physical organic chemistry and the synthesis of natural products.
From 2000 to 2005, Frantz worked in industry for pharmaceutical corporation Merck and Co. Inc. initially as a senior research scientist and then as a research fellow in the corporation's Department of Process Research. While at Merck, Frantz managed a group of process chemists in developing pre-clinical and clinical drug candidates for eventual manufacturing and distribution. He also consulted for Reata Pharmaceuticals based in Los Colinas, Texas, and Joyant Pharmaceuticals based in Dallas.
The UTSA community welcomes students to their on-campus home! Laurel Village, Chaparral Village and Alvarez Hall are home for 2,300 students during the academic year, and Move-In event kicks off the start of Roadrunner Days.
Laurel Village, Chaparral Village, Alvarez Hall, Main Campus
The College of Engineering hosts this seminar featuring Jeff Adams, Southwest Zone Quality Manager, Siemens Building Technologies Division. The event is free and open to the public.
Engineering Building (EB 3.04.30), Main Campus
This is a terrific opportunity for incoming transfer students to network with staff that serve our veteran, non-traditional, and transferring students, as well as meet transfer peer mentors who can help answer questions about UTSA.
Main Building ground floor lobby, Main Campus
After a day full of moving and getting settled into their new UTSA home, students and their families can have some refreshments and snacks at the Welcome Back Reception. The event tops off with the premiere performance of the Spirit of San Antonio, UTSA's Marching Band.
University Center Paseo, Main Campus
Can you survive the library wilderness? As a part of Roadrunner Days, UTSA Libraries is hosting a mobile adventure for you to play and find out more about the library!
John Peace Library, 2nd floor, Main Campus
Come meet your UTSA Volleyball Team as they gear up for the 2017 season! The game begins at 5 p.m. then the team will hold an autograph and photo session after the game.
Convocation Center, Main Campus
This engaging discussion pulls back the covers on hooking up, clarifying when it’s actually sexual violence and how bystanders can protect potential victims from predators.
University Center, Retama Auditorium (UC 2.02.02), Main Campus
Late Night at the Rec is an awesome UTSA tradition that transforms a standard information session into an exciting night of fun. At this annual event, you’ll be able to learn about our facilities, recreation programs, and wellness services offered at Main and Downtown Campuses.
Recreation and Wellness Center, Main Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
To be a premier public research university, providing access to educational excellence and preparing citizen leaders for the global environment.
We encourage an environment of dialogue and discovery, where integrity, excellence, inclusiveness, respect, collaboration and innovation are fostered.