(July 1, 2010) Doug E. Frantz, UTSA assistant professor of chemistry in the College of Sciences, has received the Max and Minnie Tomerlin Voelcker Fund 2010 Young Investigator Award, which includes $450,000 over the next three years to propel Frantz's medicinal chemistry research program. This is the first time a UTSA researcher will be honored with the award, which recognizes and supports promising medical research that has the potential to have a significant impact on patient care.
"By supporting research in its own backyard, the Voelcker Fund is providing a great opportunity to San Antonio medical researchers and particularly UTSA," said UTSA President Ricardo Romo. "With the outstanding support and leadership of community partners like the Voelcker Fund, UTSA will achieve premier research university status at a much faster pace."
In 2009, the Voelcker Fund began to present the award annually to assistant professors making significant research contributions that advance clinical treatment in five key areas. The target areas include heart disease, cancer, arthritis, muscular dystrophy and maculative degeneration of the retina.
"The purpose of the Voelcker Fund is to elevate research to cure targeted diseases. We are impressed with the level and focus of the scientific research being conducted by Dr. Frantz," said Voelcker Fund trustee Banks M. Smith.
Over the long term, Frantz and collaborators Jay Schneider and Jenny Hsieh of the University of Texas Southwestern Medical Center at Dallas will discover, synthesize and test libraries of small drug-like molecules that target stem cells with the potential to treat heart disease and brain cancer. In the area of heart disease, Frantz is working to identify molecules that will nudge adult stem cells to grow into new heart muscle cells instead of generating scar tissue after a heart attack.
In brain cancer, his research involves the discovery of new molecules that will turn cancerous stem cells into normal benign neurons. Currently, the researchers are targeting two classes of molecules, isoxazoles and pyrazoles, which have demonstrated success in inducing stem cells to become heart cells and neurons and have been published for the scientific community to review.
The research we are conducting in the laboratory is perfectly aligned with the broader issues of treating cardiovascular disease and cancer by combining stem cells and medicinal chemistry, said Frantz. I am extremely grateful to the trustees of the Voelcker Fund for recognizing the potential of this research and generously supporting my laboratory's research program. In addition to advancing our research, the funds support will provide undergraduates and graduate students with the opportunity to gain valuable laboratory experience at the interface of chemistry and biology and contribute to the development of therapeutic solutions for a variety of diseases.
Frantz joined UTSA in 2009 from UT Southwestern Medical Center, where he was an assistant research professor and served as director of the medical center's synthetic chemistry core facility from 2005 to 2009. At the medical center, he focused on the development of new methods in organic synthesis, medicinal chemistry, physical organic chemistry and the synthesis of natural products.
From 2000 to 2005, Frantz worked in industry for pharmaceutical corporation Merck and Co. Inc. initially as a senior research scientist and then as a research fellow in the corporation's Department of Process Research. While at Merck, Frantz managed a group of process chemists in developing pre-clinical and clinical drug candidates for eventual manufacturing and distribution. He also consulted for Reata Pharmaceuticals based in Los Colinas, Texas, and Joyant Pharmaceuticals based in Dallas.
The Department of Biology and the Be the Match Team will collaborate to engage and educate our students in the importance of a life saving donation through peripheral blood stem cells and a marrow harvest.
UC Paseo and Central Plaza, Main Campus
UTSA welcomes the Italian-born duo Bandini-Chiacchiaretta. They've toured the world performing Argentine Tango music on guitar and bandoneon, the instrument of Astor Piazzolla. Tickets are $10 or free with UTSA Student I.D.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
This an annual event is open to any student who wants to participate It includes a presentation about current events and issues involving East Asia. This event is meant to deepen understanding and to raise awareness of what is currently happening in East Asia.
Business Building, University Room (BB 2.06.04), Main Campus
Join the Women’s Studies Institute and Women’s Studies Program as we celebrate our fourteenth year of Women’s History Month at UTSA. During our program, we will award Olga Madrid as the 2017 Women’s Advocate of the Year.
H-E-B University Center, Travis Room (HUC 2.202), Main Campus
Solomon’s House, presented by Sara Cusimano Miles, explores the collections repository of the Anniston Museum of Natural History in Alabama. It's free and open to the public.
Arts Building (ARTS 3.01.18 B), Main Campus
Dr. Treva Lindsey is an associate professor at The Ohio State University. Dr. Lindsey’s area of expertise includes black feminist theory, women’s history, and popular culture. This lecture is free and open to the public.
H-E-B University Center Ballroom (HUC 1.106), Main Campus
Bruising for Besos is an art film and intimate character study of Yoli—a charismatic Xicana lesbian making familia in a queer/trans people of color scene in Los Angeles. This film contains content not suitable for people under 18.
H-E-B University Center Ballroom (HUC 1.106), Main Campus
The UTSA community is invited to participate in the 9th Annual Roadrunner Remembrance. Roadrunner Remembrance is a day of remembrance honoring members of our community (students, faculty, staff and alumni) who have passed away during the previous year.
University Center Retama Auditorium (UC 2.02.02), Main Campus
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