(July 2, 2010)--Karl Klose, director of the UTSA South Texas Center Emerging Infectious Diseases (STCEID), and Bernard Arulanandam, associate dean of research for scientific innovation in the UTSA College of Sciences, have been granted a U.S. patent for developing a process to create a vaccine for the deadly tularemia infection.
Tularemia, caused by the highly infectious bacterium Francisella tularensis, can cause serious disease in humans. F. tularensis is carried primarily by animals such as rabbits and rarely causes human infections, but when breathed in through the lungs, the disease can be fatal. Because of this, F. tularensis is considered a potential bioweapon.
"We developed what is called a 'live attenuated vaccine,' by removing Francisella's IglD gene, which is critical for the bacteria to be able to survive and grow inside infected cells," said Klose. "In a series of studies over three years, we characterized the IglD gene, knocked it out, and observed that the crippled bacterium was able to act as an effective vaccine by inducing an immune response without causing tularemia. This research is a promising advance in our attempts to develop a vaccine against this potential bioweapon."
F. tularensis is one of many organisms the researchers in the STCEID are investigating with an eye for vaccine development. Researchers are also working on vaccines for Valley Fever, Lyme disease and anthrax.
As UTSA continues to move toward Tier One research status, it has developed an increased focus on innovation, commercialization and technology transfer.
"Last year, UTSA signed its first commercial license to develop a chlamydia vaccine with pharmaceutical company Merck based on research from our South Texas Center for Emerging Infectious Diseases and the Department of Microbiology and Immunology at the University of Texas Health Science Center at San Antonio," said Arulanandam. "We are hopeful that the science behind this new patent for Francisella will spur further insight into the creation of an effective vaccine against this pathogen."
The South Texas Center for Emerging Infectious Diseases (STCEID) focuses on research in molecular microbiology, immunology, medical mycology, virology, microbial genomics, vaccine development and biodefense. The center also provides hands-on training to undergraduate and graduate students who intend to pursue careers in science and technology. Working with the UTSA College of Sciences Department of Biology, center faculty have established an undergraduate academic track in microbiology, a master's program in biology and biotechnology and a Ph.D. program in cell and molecular biology.
The CACP 2016-2017 Speaker Series continues with architect and writer Jason Griffiths of the University of Arizona and Jason Griffiths Architecture. His practice is based on a multidisciplinary approach.
Buena Vista Building, Aula Canaria Auditorium (BVB 1.328), Downtown Campus
UTSA's Department of Music hosts Dr. David Huron from Ohio State University as part of the Donald Hodges lecture series. Huron is a Canadian arts and humanities distinguished professor at Ohio State University.
John Peace Library, UTSA Faculty Center, (JPL 4.04.22), Main Campus
The UTSA community is encouraged to donate blood and save a life. Donors will also receive a free t-shirt.
H-E-B University Center parking lot, Main Campus
Dr. Stephanie Westney (violin) presents a concert of Mozart compositions as performed by herself and other talented musicians from the university and surrounding area. This concert is free and open to the public.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The Student Center for Community Engagement and Inclusion annually hosts a Volunteer Opportunities Fair to allow students, faculty and staff to learn about volunteer and service-learning opportunities in the San Antonio area.
University Center, 1st floor corridor, Main Campus
Join the conversation about the experiences of military-connected families in transition. Free parking in the Cattleman Square (along Buena Vista Street). The event is free and open to the public.
Frio Street Building, Riklin Auditorium (FS 1.406), Downtown Campus
School district superintendents and other district leaders responsible for bilingual and ESL programs' administration and accountability learn about cultural literacy, language, and diversity in the community.
Recruiters from across the STEM fields will be present with full-time, part-time and/or internship opportunities. Dress professional and bring plenty of resumes.
Convocation Center, Main Campus
Recruiters from across all fields looking to hire students with all different majors will be present at this event looking to hire for their full-time and/or internship opportunities. Professional dress is required. Bring plenty of resumes.
Convocation Center, Main Campus
The Civic Engagement Summit is an opportunity to celebrate and showcase UTSA's commitment to civic engagement through a myriad of efforts by students, faculty and staff, highlighting the significant ways the university impacts the local community.
H-E-B University Center Ballroom, (HUC 1.104), Main Campus
The Department of Demography presents Dr. Rodolfo Cruz Peñeiro of El Colegio de la Frontera Norte. His presentation is titled "Changes in the Migratory Dynamics of the Northern Mexican Border." This event is free and open to the public.
Monterrey Bldg., (MNT 3.240), UTSA Downtown Campus
Grab your friends, family, kids and dog for this annual fun run on the UTSA Main Campus benefititng the UTSA Alumni Association.
Convocation Center, Main Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
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