(July 2, 2010)--Karl Klose, director of the UTSA South Texas Center Emerging Infectious Diseases (STCEID), and Bernard Arulanandam, associate dean of research for scientific innovation in the UTSA College of Sciences, have been granted a U.S. patent for developing a process to create a vaccine for the deadly tularemia infection.
Tularemia, caused by the highly infectious bacterium Francisella tularensis, can cause serious disease in humans. F. tularensis is carried primarily by animals such as rabbits and rarely causes human infections, but when breathed in through the lungs, the disease can be fatal. Because of this, F. tularensis is considered a potential bioweapon.
"We developed what is called a 'live attenuated vaccine,' by removing Francisella's IglD gene, which is critical for the bacteria to be able to survive and grow inside infected cells," said Klose. "In a series of studies over three years, we characterized the IglD gene, knocked it out, and observed that the crippled bacterium was able to act as an effective vaccine by inducing an immune response without causing tularemia. This research is a promising advance in our attempts to develop a vaccine against this potential bioweapon."
F. tularensis is one of many organisms the researchers in the STCEID are investigating with an eye for vaccine development. Researchers are also working on vaccines for Valley Fever, Lyme disease and anthrax.
As UTSA continues to move toward Tier One research status, it has developed an increased focus on innovation, commercialization and technology transfer.
"Last year, UTSA signed its first commercial license to develop a chlamydia vaccine with pharmaceutical company Merck based on research from our South Texas Center for Emerging Infectious Diseases and the Department of Microbiology and Immunology at the University of Texas Health Science Center at San Antonio," said Arulanandam. "We are hopeful that the science behind this new patent for Francisella will spur further insight into the creation of an effective vaccine against this pathogen."
The South Texas Center for Emerging Infectious Diseases (STCEID) focuses on research in molecular microbiology, immunology, medical mycology, virology, microbial genomics, vaccine development and biodefense. The center also provides hands-on training to undergraduate and graduate students who intend to pursue careers in science and technology. Working with the UTSA College of Sciences Department of Biology, center faculty have established an undergraduate academic track in microbiology, a master's program in biology and biotechnology and a Ph.D. program in cell and molecular biology.
The annual Student Affairs Conference provides invaluable professional development opportunities for all UTSA Student Affairs staff as well as faculty and staff throughout UTSA and other local institutions.
H-E-B Student Union Ballroom (HSU 1.104), Main Campus
Campers in 9th grade through college will receive instruction and coaching on agility testing and position specific drills to refine and improve his skillset as a football player.
Recreational Field Complex, Main Campus
Inspired by UTSA's renowned Mexican Cookbook Collection, the evening features cuisine and spirits of celebrated chefs from San Antonio and Mexico.
Hotel Emma, 136 E. Grayson St., San Antonio
Experience a fun, interactive week at UTSA as new students and their families take the first steps to becoming a Roadrunner.
Various locations, Main Campus
Campers 6-12 years old will enjoy the summer learning to read, write and speak the Chinese language. They also will learn about the Chinese culture such as martial arts, painting and drawing, arts and crafts and more.
Confucius Institute at UTSA (MB 1.208), Main Campus
Campers 7th grade and up will focus on individual development with emphasis on simplifying and teaching the specific skills and movements associated with the game. Serving, passing, setting, attacking and individual defense will all be covered. In addition, team concepts will be emphasized.
Convocation Center, Main Campus
Celebrate Texas' diversity with authentic ethnic cuisine, music, dance, arts and crafts from the many countries that make up the rich heritage of Texas.
UTSA Institute of Texan Cultures, Hemisfair Campus
The 3 day, annual Department of Defense-sponsored conference brings together military and civilian practitioners from across government, industry, and academia to address the nexus of cyberspace and national security.
Business Building Liu Auditorium (BB 2.01.02), Main Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
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