(July 2, 2010)--Karl Klose, director of the UTSA South Texas Center Emerging Infectious Diseases (STCEID), and Bernard Arulanandam, associate dean of research for scientific innovation in the UTSA College of Sciences, have been granted a U.S. patent for developing a process to create a vaccine for the deadly tularemia infection.
Tularemia, caused by the highly infectious bacterium Francisella tularensis, can cause serious disease in humans. F. tularensis is carried primarily by animals such as rabbits and rarely causes human infections, but when breathed in through the lungs, the disease can be fatal. Because of this, F. tularensis is considered a potential bioweapon.
"We developed what is called a 'live attenuated vaccine,' by removing Francisella's IglD gene, which is critical for the bacteria to be able to survive and grow inside infected cells," said Klose. "In a series of studies over three years, we characterized the IglD gene, knocked it out, and observed that the crippled bacterium was able to act as an effective vaccine by inducing an immune response without causing tularemia. This research is a promising advance in our attempts to develop a vaccine against this potential bioweapon."
F. tularensis is one of many organisms the researchers in the STCEID are investigating with an eye for vaccine development. Researchers are also working on vaccines for Valley Fever, Lyme disease and anthrax.
As UTSA continues to move toward Tier One research status, it has developed an increased focus on innovation, commercialization and technology transfer.
"Last year, UTSA signed its first commercial license to develop a chlamydia vaccine with pharmaceutical company Merck based on research from our South Texas Center for Emerging Infectious Diseases and the Department of Microbiology and Immunology at the University of Texas Health Science Center at San Antonio," said Arulanandam. "We are hopeful that the science behind this new patent for Francisella will spur further insight into the creation of an effective vaccine against this pathogen."
The South Texas Center for Emerging Infectious Diseases (STCEID) focuses on research in molecular microbiology, immunology, medical mycology, virology, microbial genomics, vaccine development and biodefense. The center also provides hands-on training to undergraduate and graduate students who intend to pursue careers in science and technology. Working with the UTSA College of Sciences Department of Biology, center faculty have established an undergraduate academic track in microbiology, a master's program in biology and biotechnology and a Ph.D. program in cell and molecular biology.
The UTSA Institute for P-20 Initiatives hosts this free breakfast to kick off a new school year and a new opportunity to volunteer at mentoring organizations in our community.
Whataburger, 8680 Fourwinds Dr., San Antonio
As part of the International Cooking Series, the experts in the UTSA Demo Kitchen will show you how to make this stuffed bread Latin dish. Register for this cooking demo here.
Recreation Wellness Center Demo Kitchen, Main Campus
UTSA's annual sustainability festival, showcases the university’s and the City of San Antonio’s progress on researching and developing sustainable solutions to improve the quality life for future generations.
H-E-B University Center Ballroom (HUC 1.104), Main Campus
The institute will feature a performance from Eva Ybarra, the “Queen of the Accordion.” Manuel Medrano will premiere a documentary on Ybarra’s career. Two people receive free admission with a voucher available here.
Institute of Texan Cultures, Hemisfair Campus
Get involved and register to vote. Click on the link to find out the locations on the Main and Downtown Campuses.
Multiple locations on the Main and Downtown Campuses
Learn about products and services available for studying, working, and making it to graduation! Speak directly to OIT managers, provide feedback on UTSA tech, and have your voice heard! Lunch and OIT gear provided. RSVP at: www.utsa.edu/oit/sic.
University Center, Denman Ballroom (2.01.28), Main Campus
Come meet the candidates looking to take home the crown as Mr. and Ms. UTSA 2017-2018. This is your opportunity to hear the candidates platform and learn how they plan to represent and transform UTSA.
University Center, Retama Auditorium (UC 2.02.02), Main Campus
UTSA's Friends of Shakespeare hosts this annual performance seried by Actors from the London Stage, Sept. 27, 29 and 30 at 7:30 p.m.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
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