Thursday, October 08, 2015


$200K grant to aid UTSA chemist Donald Kurtz in researching cancer therapy


Iron (left) attacks cancer cell

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(Nov. 30, 2010)--Lutcher Brown Distinguished Chair Donald Kurtz in the UTSA Department of Chemistry has been selected to receive $199,906 from the Cancer Prevention and Research Institute of Texas (CPRIT) to develop a novel approach to delivering iron at toxic levels to kill cancer cells and tumors. The two-year research project is considered "High Impact High Risk" and if successful could have a tremendous impact on cancer therapy.

"Iron is essential for all cells in the body to function properly and is safe up to certain levels -- however, the cells' iron transfer process is highly regulated," said Kurtz. "If we overload cells or tissues with iron, it becomes toxic. Our goal is to develop a method for delivering iron at toxic levels specifically to cancer cells."

Over the next two years, Kurtz and his research team will focus on developing a photochemical or light-activated cancer therapy. A nano-scale protein scaffold filled with approximately 2,000 iron atoms in its hollow center will drive the treatment. The scaffold will include peptides on its outer shell that will allow it to be recognized specifically by cancer cells. The peptides would make the scaffold bind to the cancer cells like Velcro.

Once researchers deliver the iron-loaded scaffold to cancer cells, they will zap the scaffold with tissue-penetrating, near-infra-red light. The light treatment will cause the scaffold to release its iron into the cells. The released iron will induce the production of free radicals, which, at sufficiently high levels, will overwhelm the cell's anti-oxidant capacity -- thereby killing the cells. The peptide on the outer shell of the protein scaffold can be varied to target specific types of cancers such as breast or prostate.

"The basic idea is to use light as the trigger to shoot iron out of our protein scaffold and into the cancer cells," said Kurtz. "Think of it as shooting iron bullets to kill cancer." Kurtz joined UTSA's faculty in 2006 after serving 20 years on the chemistry faculty at the University of Georgia. He is a specialist in bioinorganic chemistry and studies metalloenzymes such as non-heme iron enzymes at the molecular level.

Established by Texas voters in 2007, CPRIT will invest up to $3 billion for groundbreaking cancer research, prevention programs and services in Texas.



Oct. 10, 8:30 a.m. - 3 p.m.

UTSA CITE Technology Entrepreneurship Boot Camp

Kickstart your career as an entrepreneur at the UTSA Center for Innovation, Technology and Entrepreneurship Boot Camp.
Business Building, Richard S. Liu Auditorium (BB 2.01.02), Main Campus

Oct. 14, 5:30 p.m.

Architecture as Rendered Society

The UTSA College of Architecture, Construction and Planning, in partnership with AIA San Antonio’s Latinos in Architecture, presents architect Andrés Jaque, founder of the Office for Political Innovation, an architectural practice dually based in New York and Madrid.
Buena Vista Building, Aula Canaria Lecture Hall (BV 1.328), Downtown Campus

Oct. 15, 6 p.m.

Take Back the Night 2015

The UTSA Women’s Studies Institute invites you to Take Back the Night, an international initiative to raise awareness and empower survivors while educating allies through a march, poetry, and testimonios. This is a gender-inclusive movement to shatter the silence surrounding sexual and domestic violence.
Sombrilla Plaza, Main Campus

Oct. 20-21, 9 a.m. - 3 p.m.

SECC Book Sale

Looking for a good read? Shop for yourself or for gifts and help change a life at the same time. Browse and buy children’s stories, novels and more at the 2015 SECC Book Sale.
Sombrilla Plaza, Main Campus

Oct. 22, 6 p.m.

Phi Kappa Phi Last Lecture

What would Dr. John Bartkowski say if it were his last lecture? The UTSA professor of sociology will speak about “The Power of Listening” in this annual event sponsored by the UTSA chapter of Phi Kappa Phi. A reception will follow.
Denman Room (UC 2.201.28), Main Campus

Oct. 27, 11:30 a.m.

Lecture by Composer Larry Groupe

The UTSA Music Department presents Emmy-award winning Composer Larry Groupe. Groupe has composed music for films such as "The Contender," "Straw Dogs" and "Miami Vice," and TV shows such as "Star Trek: The Next Generation," "Ren and Stimpy" and "American Gladiators." Lecture is free and open to the public.
Arts Building (ART 2.03.15-18), Main Campus

Oct. 29, 5:30 p.m.

White Bound: Nationalists, Anti-Racists and the Shared Meanings of Race

The Dean's Distinguished Lecture Series continues with Dr. Matthew Hughey, a scholar of race, racism and racial inequality.
Buena Vista Building (BV 1.328), Downtown Campus

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Renowned violinist Stan Renard plants roots at UTSA

Performer, conductor will teach multidisciplinary courses in music marketing

Did You Know?

UTSA writes the book on all-digital libraries

As touch screens and e-books demand more and more attention from both casual readers and scholars, many people say the handwriting is on the wall for the printed page.

At UTSA, the handwriting is on the wall for a library that doesn't have any printed books.

Since March 2010, the bookless library in the Applied Engineering and Technology Building has given UTSA students an innovative way to read, research and work with each other to solve problems.

With ultra-modern furniture and a décor featuring desktop computers, scanners and LCD screens, the AET Library is designed to engage students in an online format. But it also offers group study niches and study rooms with whiteboards and glass walls on which students can write. The space encourages teamwork, communications and problem solving for the next generation of scientists and professional engineers.

Did you know? The UTSA AET Library is the nation's first completely bookless library on a college or university campus. It served as a model for Bexar County's first-in-the-nation public bookless library system and one of its branches, the Dr. Ricardo Romo BiblioTech.

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