Wednesday, October 07, 2015


UTSA tularemia researchers granted U.S. patent for work on bacterium


Tularemia bacteria

Share this Story

(Feb. 9, 2012) -- A group of researchers in the UTSA South Texas Center for Emerging Infectious Diseases (STCEID) was granted a United States patent from the U.S. Patent and Trademark Office for its work on Francisella tularensis (F. tularensis), the bacterium that causes the human disease tularemia (or rabbit fever). While natural cases of tularemia are relatively rare, F. tularensis can be fatal when acquired through the lungs, and thus this organism is considered a potential biothreat agent.

UTSA researchers James Chambers, professor of biochemistry; Jieh-Juen Yu, research assistant professor; Neal Guentzel, professor of microbiology; Bernard Arulanandam, Jane and Roland Blumberg Professor in Biology and associate dean of research for scientific innovation; and Karl Klose, professor of microbiology and STCEID director; have studied F. tularensis for years. The team led by Arulanandam and Chambers found that Francisella degrades alkaline phosphatase (AP) during infection, and the distinctive degradation can be used as a diagnostic tool to reveal the presence of the bacteria.

"The South Texas Center for Emerging Infectious Diseases is focused on developing new diagnostics, therapeutics and vaccines to reduce the impact of infectious organisms on the human population," said Klose. "Tularemia is a difficult disease to diagnose, due to its infrequent appearance in the clinical setting, yet rapid diagnosis may be critical for effective intervention during a bioterrorist event. This patent may lead to better diagnostics and possibly even novel therapeutics for tularemia."

In 2010, STCEID researchers also were awarded a patent for developing a tularemia vaccine composed of a live crippled Francisella bacterium unable to cause disease but able to induce protection against infection.

The STCEID focuses on research in molecular microbiology, immunology, medical mycology, virology, microbial genomics, vaccine development and biodefense, and studies the organisms that cause Valley Fever, Lyme disease, anthrax, cholera and other infectious diseases. The center also provides hands-on training to high school, undergraduate and graduate students who intend to pursue careers in science and technology.

Working with the Department of Biology in the UTSA College of Sciences, center faculty have established an undergraduate academic track in microbiology, a master's program in biology and biotechnology, and a Ph.D. program in cell and molecular biology. In 2011, the STCEID established a Center of Excellence in Infection Genomics with funding from the Department of Defense.

"The push to commercialize UTSA intellectual property for the benefit of the general public is one of the things that will help UTSA become a Tier One research institution," said Arulanandam. "Those discoveries lead to commercial licenses, income that will give our researchers and others across the university the opportunity to work on human health challenges facing today's society."





Oct. 5, 6 p.m.

Film Screening: The Head of Joaquin Murrieta by John Valadez

The Mexican American Studies Program will host a screening of this irreverent, entertaining and often disturbing tale that uses both fiction and documentary story telling devices to tear open a painful and long ignored history: the lynching of Mexican Americans in the southwest.
Buena Vista Building Aula Canaria (BV 1.328), Downtown Campus

Oct. 6, 3 p.m.

State of the University

Join President Ricardo Romo as he gives his address to the UTSA community.
H-E-B University Center Ballroom (UC 1.104), Main Campus

Oct. 7, 6:30 p.m.

The Impact of the 84th Texas Legislative Session on Public Schools: Any Rain in Sight or Are Those Smoke Clouds on the Horizon?

Join the College of Education and Human Development's Center for Educational Leadership, Policy and Professional Development for a discussion about what passed and what didn't in the last legislative session and what it means for Bexar County Public Schools. 
Durango Building Southwest Room (DB 1.124), Main Campus

Oct. 8, 10 a.m.

Graduate Fair

Graduate School representatives from across the country will provide information on options after earning a bachelor's degree. Students, alumni and community members are welcome.
University Center Retama Galleria, Main Campus

Oct. 10, 8:30 a.m. - 3 p.m.

UTSA CITE Technology Entrepreneurship Boot Camp

Kickstart your career as an entrepreneur at The University of Texas at San Antonio’s Center for Innovation, Technology and Entrepreneurship (CITE) Technology Entrepreneurship Boot Camp.
Business Building, Richard S. Liu Auditorium (BB 2.01.02), Main Campus

Oct. 14, 5:30 p.m.

Architecture as Rendered Society

The UTSA College of Architecture, Construction and Planning, in partnership with AIA San Antonio’s Latinos in Architecture, presents architect Andrés Jaque, founder of the Office for Political Innovation, an architectural practice dually based in New York and Madrid.
Buena Vista Building, Aula Canaria Lecture Hall (BV 1.328), Downtown Campus

Oct. 20-21, 9 a.m. - 3 p.m.

SECC Book Sale

Looking for a good read? Shop for yourself or for gifts and help change a life at the same time. Browse and buy children’s stories, novels and more at the 2015 SECC Book Sale.
Sombrilla Plaza, Main Campus

Oct. 27, 11:30 a.m.

Lecture by Composer Larry Groupe

The UTSA Music Department presents Emmy-award winning Composer Larry Groupe. Groupe has composed music for films such as "The Contender," "Straw Dogs" and "Miami Vice," and TV shows such as "Star Trek: The Next Generation," "Ren and Stimpy" and "American Gladiators." Lecture is free and open to the public.
Arts Building (2.03.15-18), Main Campus

Other Calendars
» UTSA Events | » Academic | » Institute of Texan Cultures

Submit an Event

Meet a Roadrunner

UTSA student tackles the psychology of breast cancer

Kristen Rosen is developing technology to help breast cancer patients’ quality of life

Did You Know?

UTSA writes the book on all-digital libraries

As touch screens and e-books demand more and more attention from both casual readers and scholars, many people say the handwriting is on the wall for the printed page.

At UTSA, the handwriting is on the wall for a library that doesn't have any printed books.

Since March 2010, the bookless library in the Applied Engineering and Technology Building has given UTSA students an innovative way to read, research and work with each other to solve problems.

With ultra-modern furniture and a décor featuring desktop computers, scanners and LCD screens, the AET Library is designed to engage students in an online format. But it also offers group study niches and study rooms with whiteboards and glass walls on which students can write. The space encourages teamwork, communications and problem solving for the next generation of scientists and professional engineers.

Did you know? The UTSA AET Library is the nation's first completely bookless library on a college or university campus. It served as a model for Bexar County's first-in-the-nation public bookless library system and one of its branches, the Dr. Ricardo Romo BiblioTech.

Read More »

UTSA's Mission

The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.

UTSA's Vision

To be a premier public research university, providing access to educational excellence and preparing citizen leaders for the global environment.

UTSA's Core Values

We encourage an environment of dialogue and discovery, where integrity, excellence, inclusiveness, respect, collaboration and innovation are fostered.

Connect with UTSA News


Related Links

Back to Top

2015 © The University of Texas at San Antonio  |  Produced by University Communications and Marketing