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UTSA tularemia researchers granted U.S. patent for work on bacterium

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Tularemia bacteria

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(Feb. 9, 2012) -- A group of researchers in the UTSA South Texas Center for Emerging Infectious Diseases (STCEID) was granted a United States patent from the U.S. Patent and Trademark Office for its work on Francisella tularensis (F. tularensis), the bacterium that causes the human disease tularemia (or rabbit fever). While natural cases of tularemia are relatively rare, F. tularensis can be fatal when acquired through the lungs, and thus this organism is considered a potential biothreat agent.

UTSA researchers James Chambers, professor of biochemistry; Jieh-Juen Yu, research assistant professor; Neal Guentzel, professor of microbiology; Bernard Arulanandam, Jane and Roland Blumberg Professor in Biology and associate dean of research for scientific innovation; and Karl Klose, professor of microbiology and STCEID director; have studied F. tularensis for years. The team led by Arulanandam and Chambers found that Francisella degrades alkaline phosphatase (AP) during infection, and the distinctive degradation can be used as a diagnostic tool to reveal the presence of the bacteria.

"The South Texas Center for Emerging Infectious Diseases is focused on developing new diagnostics, therapeutics and vaccines to reduce the impact of infectious organisms on the human population," said Klose. "Tularemia is a difficult disease to diagnose, due to its infrequent appearance in the clinical setting, yet rapid diagnosis may be critical for effective intervention during a bioterrorist event. This patent may lead to better diagnostics and possibly even novel therapeutics for tularemia."

In 2010, STCEID researchers also were awarded a patent for developing a tularemia vaccine composed of a live crippled Francisella bacterium unable to cause disease but able to induce protection against infection.

The STCEID focuses on research in molecular microbiology, immunology, medical mycology, virology, microbial genomics, vaccine development and biodefense, and studies the organisms that cause Valley Fever, Lyme disease, anthrax, cholera and other infectious diseases. The center also provides hands-on training to high school, undergraduate and graduate students who intend to pursue careers in science and technology.

Working with the Department of Biology in the UTSA College of Sciences, center faculty have established an undergraduate academic track in microbiology, a master's program in biology and biotechnology, and a Ph.D. program in cell and molecular biology. In 2011, the STCEID established a Center of Excellence in Infection Genomics with funding from the Department of Defense.

"The push to commercialize UTSA intellectual property for the benefit of the general public is one of the things that will help UTSA become a Tier One research institution," said Arulanandam. "Those discoveries lead to commercial licenses, income that will give our researchers and others across the university the opportunity to work on human health challenges facing today's society."


 

 

 

 

Events
Feb. 5, 6:15 p.m.

First Friday Stargazing

The UTSA Department of Physics and Astronomy's Curtis Vaughan Observatory will offer free stargazing for the public beginning on top of the 4th floor of the Flawn Science Building. Experienced astronomers will be on hand to show a variety of astronomical objects and answer any questions. This event is free and open to the public, so feel free to invite friends and family.
Curtis Vaughan Observatory

Feb. 6, All Day

10th annual San Antonio Writing Project Teachers' Conference

This year's keynote speaker is Donalyn Miller, author of The Book Whisper. The event will feature breakout sessions and a presentation by the Creative Writers from North East School of the Arts. The event is free and open to all teachers from Pre-K through university level. Attendees can earn a certificate for 3 hours of Professional Development Credit.
Riklin Auditorium (FS1.406), Downtown Campus

Feb. 9, 11 a.m. - 1 p.m. & 6 - 9 p.m.

Rowdy Gras 2016

The UTSA community is invited to attend the 3rd annual Rowdy Gras celebration! This year Rowdy Gras includes a daytime event from 11 a.m. -1 p.m. with a free food tasting and music on the UC Paseo. The main event takes place from 6 - 9 p.m. in the UC Lawn. The event includes free food, live jazz music, activities and giveaways.
University Center Paseo & Lawn, UTSA Main Campus

Feb. 10, 5:30 p.m.

UTSA College of Architecture, Construction and Planning 2015-16 Speaker Series

The UTSA College of Architecture, Construction and Planning’s 2015-16 Speaker Series continues with Dana Cuff, Ph.D., a professor of architecture and urbanism at the University of California, Los Angeles. In her talk, Cuff will discuss new forms of “studio” and new types of practices. Free and open to the public.
Aula Canaria Lecture Hall (BV 1.328), UTSA Downtown Campus

Feb. 13, 10 a.m. - 5 p.m.

29th annual Asian Festival - Year of the Monkey

The UTSA Institute of Texan Cultures invites Texas and Texans to the Asian Festival. What began as a traditional family reunion for the Chinese New Year has expanded to include other Asian communities and participants, showcasing their unique culture and traditions.
The UTSA Institute of Texan Cultures

Feb. 13, 1 p.m.

2016 Interdisciplinary Studies Colloquium

Join the UTSA Department of Interdisciplinary Learning and Teaching in celebrating interdisciplinary inquiry at the 2016  Interdisciplinary Studies Colloquium.  The colloquium will include a panel of faculty and recent doctoral graduate and a showcase of the best IDS undergraduate inquiry projects of the year 2015. The event is free and open to the public.
Business Building (BB 2.06.04), UTSA Main Campus

Feb. 23, 5:30 p.m.

African-American Social Welfare Pioneers Responding to Community Needs

The UTSA College of Public Policy presents the Dean's Distinguished Lecture Series featuring Dr. Iris Carlton-LaNey, Professor of the School of Social Work at the University of North Carolina-Chapel Hill. Dr. Iris Carlton LaNey will speak to the UTSA community about the role and impact of African-Americans in the social work profession.
Buena Vista Theater (BV 1.326), Downtown Campus

Feb. 23, 7 p.m.

Presentation and Book Signing with Luis Carlos Montalvan

Please join us for a presentation and book signing by Luis Carlos Montalván (Fmr. Capt., USA), author of the New York Times Bestseller Until Tuesday and the international award-winning childrens book Tuesday Tucks Me In. His books will be available for purchase at the UTSA Bookstore. This event is free and open to the public.
Southwest Room (DB 1.124), Downtown Campus

Feb. 25, 6 p.m.

12th Annual Black Heritage Gala

The 12th Annual Black Heritage Gala is a formal event which includes a student performance, keynote remarks by Michael Brown, an award presentation, dinner and dancing. Tickets are $10 for UTSA students and $15 for all other guests. Tickets are on sale now at Roadrunner Express. Contact (210) 458-4770 for more information.
H-E-B University Center Ballroom, Main Campus

Feb. 27, 9 a.m.

Cultural Contrasts in Latin America

The UTSA Institute of Texan Cultures will host a free workshop focusing on teaching Latin American culture and geography for students seeking their teacher certification. The workshop includes free resources for teaching Latin American subject matter as well as presentations on language, identity, music, geography, and political and developmental history, and a special educators’ tour of the museum’s Los Tejanos exhibit. Free with registration.
The UTSA Institute of Texan Cultures (ITC 3.01.02)


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