Tuesday, October 13, 2015


UTSA alumna, advisers launch Cardiovate to prevent aortic aneurysm ruptures


Cardiovate device

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(May 23, 2012) ---University of Texas at San Antonio (UTSA) alumna Jordan Kaufmann, Ph.D.; UTSA College of Engineering Dean Mauli Agrawal; and UT Medicine San Antonio cardiologist Steven Bailey, M.D., have launched Cardiovate, a technology start-up that will offer a new and much-needed cardiovascular stent-graft to prevent aneurysm leakage following cardiovascular surgeries.

Kaufmann, an alumna of the UTSA College of Engineering's Department of Biomedical Engineering, developed the stent-graft as part of her doctoral research with UTSA's Agrawal and Bailey, division chief for cardiology in the School of Medicine of the UT Health Science Center San Antonio.

"To take an idea that we were throwing around and develop it all the way to a product for a start-up company has been an incredible opportunity," said Kaufmann. "The path epitomized both translational research and multidisciplinary studies, which has been a great educational experience."

Approximately 1.2 million people in the United States suffer from an abdominal aortic aneurysm. Aneurysm rupture is the nation's 13th leading cause of death. Surgeons perform approximately 65,000 abdominal aortic aneurysm repairs annually.

However, in a surgical repair procedure called endovascular aneurysm repair, one of every six patients experiences stent-graft leakage from traditional stent-grafts in the month following surgery. Additionally, 20 to 30 percent of patients require additional corrective surgery as much as six to eight years later.

While pursuing her doctoral degree in biomedical engineering at UTSA under the supervision of Agrawal and Bailey, Kaufmann developed a unique scaffold, which promotes tissue formation. The product, called a tissue-engineering scaffold for aneurysm repair (TESAR), creates a tissue barrier between the blood and the aneurysm after it is implanted.

The scaffold promotes healthy tissue formation to repave the aneurysm wall. Once the scaffold is in place, the aneurysm stops expanding and the risk of rupture decreases. After new tissue is in place, the scaffold degrades and is safely reabsorbed by the body.

Cardiovate's TESAR stent-graft has been shown in the laboratory to reduce post-operative complications during aneurysm repair surgery such as the need for additional corrective surgeries following the initial procedure. Also, the natural tissue is a better match for biological healing than the materials found in traditional stent-grafts.

Between now and March 2013, Kaufmann, Agrawal and Bailey will work together to refine the manufacturing of the TESAR, and they will test it to ensure it conforms to the highest safety and quality standards.

"The launch of Cardiovate is testament to the phenomenal technology being created in UTSA labs and the great entrepreneurial ecosystem the university fosters," said Cory Hallam, director of the UTSA Center for Innovation and Technology Entrepreneurship. "These types of spin-offs have the ability to save lives, create jobs, build multi-million-dollar markets and significantly reduce health-care costs caused by complications that arise with the existing technologies."

The scholars expect to make the product available for licensing to a larger company in 2013. Ideally, it then would be on the market for vascular surgeons to use shortly after being evaluated by the FDA.



Oct. 14, 5:30 p.m.

Architecture as Rendered Society

The UTSA College of Architecture, Construction and Planning, in partnership with AIA San Antonio’s Latinos in Architecture, presents architect Andrés Jaque, founder of the Office for Political Innovation, an architectural practice dually based in New York and Madrid.
Buena Vista Building, Aula Canaria Lecture Hall (BV 1.328), Downtown Campus

Oct. 15, 6 p.m.

Take Back the Night 2015

The UTSA Women’s Studies Institute invites you to Take Back the Night, an international initiative to raise awareness and empower survivors while educating allies through a march, poetry, and testimonios. This is a gender-inclusive movement to shatter the silence surrounding sexual and domestic violence.
Sombrilla Plaza, Main Campus

Oct. 19, 10 a.m.-6 p.m.

UTSA Grad Fest Fall 2015

Grad Fest is an event designed to prepare you for commencement while celebrating your achievement. You will have the opportunity to purchase commencement regalia, order class rings, diploma frames, explore graduate school opportunities, learn about successful Stafford loan repayment and discuss career outcomes.
H-E-B University Center Ballroom, Main Campus

Oct. 20, 10 a.m.-3 p.m.

UTSA Grad Fest Fall 2015

Grad Fest is an event designed to prepare you for commencement while celebrating your achievement. You will have the opportunity to purchase commencement regalia, order class rings, diploma frames, explore graduate school opportunities, learn about successful Stafford loan repayment and discuss career outcomes.
H-E-B University Center Ballroom, Main Campus

Oct. 20-21, 9 a.m. - 3 p.m.

SECC Book Sale

Looking for a good read? Shop for yourself or for gifts and help change a life at the same time. Browse and buy children’s stories, novels and more at the 2015 SECC Book Sale.
Sombrilla Plaza, Main Campus

Oct. 21, 7-8:30 p.m.

Texas Water Symposium

The Texas Water Symposium will take a close look at the SAWS/Vista Ridge pipeline project. The program will feature a conversation about the regional, financial and ecological considerations of the 142-mile pipeline. The event is free and open to the public.
Main Building (MB 0.106), Main Campus

Oct. 22, 6 p.m.

Phi Kappa Phi Last Lecture

What would Dr. John Bartkowski say if it were his last lecture? The UTSA professor of sociology will speak about “The Power of Listening” in this annual event sponsored by the UTSA chapter of Phi Kappa Phi. A reception will follow.
Denman Room (UC 2.201.28), Main Campus

Oct. 27, 11:30 a.m.

Lecture by Composer Larry Groupe

The UTSA Music Department presents Emmy-award winning Composer Larry Groupe. Groupe has composed music for films such as "The Contender," "Straw Dogs" and "Miami Vice," and TV shows such as "Star Trek: The Next Generation," "Ren and Stimpy" and "American Gladiators." Lecture is free and open to the public.
Arts Building (ART 2.03.15-18), Main Campus

Oct. 29, 5:30 p.m.

White Bound: Nationalists, Anti-Racists and the Shared Meanings of Race

The Dean's Distinguished Lecture Series continues with Dr. Matthew Hughey, a scholar of race, racism and racial inequality.
Buena Vista Building (BV 1.328), Downtown Campus

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Did You Know?

UTSA writes the book on all-digital libraries

As touch screens and e-books demand more and more attention from both casual readers and scholars, many people say the handwriting is on the wall for the printed page.

At UTSA, the handwriting is on the wall for a library that doesn't have any printed books.

Since March 2010, the bookless library in the Applied Engineering and Technology Building has given UTSA students an innovative way to read, research and work with each other to solve problems.

With ultra-modern furniture and a décor featuring desktop computers, scanners and LCD screens, the AET Library is designed to engage students in an online format. But it also offers group study niches and study rooms with whiteboards and glass walls on which students can write. The space encourages teamwork, communications and problem solving for the next generation of scientists and professional engineers.

Did you know? The UTSA AET Library is the nation's first completely bookless library on a college or university campus. It served as a model for Bexar County's first-in-the-nation public bookless library system and one of its branches, the Dr. Ricardo Romo BiblioTech.

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