(May 23, 2012) ---University of Texas at San Antonio (UTSA) alumna Jordan Kaufmann, Ph.D.; UTSA College of Engineering Dean Mauli Agrawal; and UT Medicine San Antonio cardiologist Steven Bailey, M.D., have launched Cardiovate, a technology start-up that will offer a new and much-needed cardiovascular stent-graft to prevent aneurysm leakage following cardiovascular surgeries.
Kaufmann, an alumna of the UTSA College of Engineering's Department of Biomedical Engineering, developed the stent-graft as part of her doctoral research with UTSA's Agrawal and Bailey, division chief for cardiology in the School of Medicine of the UT Health Science Center San Antonio.
"To take an idea that we were throwing around and develop it all the way to a product for a start-up company has been an incredible opportunity," said Kaufmann. "The path epitomized both translational research and multidisciplinary studies, which has been a great educational experience."
Approximately 1.2 million people in the United States suffer from an abdominal aortic aneurysm. Aneurysm rupture is the nation's 13th leading cause of death. Surgeons perform approximately 65,000 abdominal aortic aneurysm repairs annually.
However, in a surgical repair procedure called endovascular aneurysm repair, one of every six patients experiences stent-graft leakage from traditional stent-grafts in the month following surgery. Additionally, 20 to 30 percent of patients require additional corrective surgery as much as six to eight years later.
While pursuing her doctoral degree in biomedical engineering at UTSA under the supervision of Agrawal and Bailey, Kaufmann developed a unique scaffold, which promotes tissue formation. The product, called a tissue-engineering scaffold for aneurysm repair (TESAR), creates a tissue barrier between the blood and the aneurysm after it is implanted.
The scaffold promotes healthy tissue formation to repave the aneurysm wall. Once the scaffold is in place, the aneurysm stops expanding and the risk of rupture decreases. After new tissue is in place, the scaffold degrades and is safely reabsorbed by the body.
Cardiovate's TESAR stent-graft has been shown in the laboratory to reduce post-operative complications during aneurysm repair surgery such as the need for additional corrective surgeries following the initial procedure. Also, the natural tissue is a better match for biological healing than the materials found in traditional stent-grafts.
Between now and March 2013, Kaufmann, Agrawal and Bailey will work together to refine the manufacturing of the TESAR, and they will test it to ensure it conforms to the highest safety and quality standards.
"The launch of Cardiovate is testament to the phenomenal technology being created in UTSA labs and the great entrepreneurial ecosystem the university fosters," said Cory Hallam, director of the UTSA Center for Innovation and Technology Entrepreneurship. "These types of spin-offs have the ability to save lives, create jobs, build multi-million-dollar markets and significantly reduce health-care costs caused by complications that arise with the existing technologies."
The scholars expect to make the product available for licensing to a larger company in 2013. Ideally, it then would be on the market for vascular surgeons to use shortly after being evaluated by the FDA.
This 3-day workshop features lectures & practical exercises designed for English-Spanish interpreters in legal settings. Hosted by the Graduate Certificate in Translation & Interpreting Studies of the Dept. of Modern Languages & Literatures.
McKinney Humanities Building (MH 3.01.28), Main Campus
The UTSA East Asia Institute hosts District 8 City Councilman Ron Nirenberg who will discuss his recent trip to China for the 8th annual Sister Cities International forum. He will discuss how these conversations help citizens connect in an increasingly global world to exchange ideas and tackle issues affecting all of us.
University Center, Denman Room (UC 2.01.28), Main Campus
Dr. Gaye Theresa Johnson, associate professor of Chicana and Chicano Studies, and African American Studies, at the University of California at Los Angeles is the guest speaker at this free, open event. Johnson is also the author of "Spaces of Conflict Sounds of Solidarity: Music, Race, and Spacial Entitlement in Los Angeles" and "Futures of Black Radicalism."
University Center, Denman Room (UC 02.01.28), Main Campus
The UTSA Consortium for Social Transformation; African American Studies Program presents guest speaker Dr. Gaye Theresa Johnson, associate professor of Chicana and Chicano Studies, and African American Studies, University of California at Los Angelesand author of "Spaces of Conflict Sounds of Solidarity: Music, Race, and Spacial Entitlement in Los Angeles" and "Futures of Black Radicalism." The event is free and open to the public.
University Center, Denman Room (UC 2.01.28), Main Campus
Grab your friends, family, kids and dog for this annual fun run on the UTSA Main Campus benefititng the UTSA Alumni Association.
Convocation Center, Main Campus
Join the Department of Interdisciplinary Learning and Teaching for the 13th annual Storytelling Festival. The festival will feature keynote speaker Carolina Quiroga-Stultz, a Colombian Storyteller and journalist. This event is free and open to the public.
Main Building, ground floor, Main Campus
The IDS Colloquium showcases the excellent scholarship done by the IDS students in the College of Education and Human Development at UTSA. In addition, this event also honors the legacy of Dr. Marian Martinello.
Business Building, University Room (BB 2.06.04), Main Campus
UTSA welcomes the Italian-born duo Bandini-Chiacchiaretta. They've toured the world performing Argentine Tango music on guitar and bandoneon, the instrument of Astor Piazzolla. Tickets are $10 or free with UTSA Student I.D.
Arts Building, Recital Hall (Arts 2.03.02), Main Campus
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