(May 23, 2012) ---University of Texas at San Antonio (UTSA) alumna Jordan Kaufmann, Ph.D.; UTSA College of Engineering Dean Mauli Agrawal; and UT Medicine San Antonio cardiologist Steven Bailey, M.D., have launched Cardiovate, a technology start-up that will offer a new and much-needed cardiovascular stent-graft to prevent aneurysm leakage following cardiovascular surgeries.
Kaufmann, an alumna of the UTSA College of Engineering's Department of Biomedical Engineering, developed the stent-graft as part of her doctoral research with UTSA's Agrawal and Bailey, division chief for cardiology in the School of Medicine of the UT Health Science Center San Antonio.
"To take an idea that we were throwing around and develop it all the way to a product for a start-up company has been an incredible opportunity," said Kaufmann. "The path epitomized both translational research and multidisciplinary studies, which has been a great educational experience."
Approximately 1.2 million people in the United States suffer from an abdominal aortic aneurysm. Aneurysm rupture is the nation's 13th leading cause of death. Surgeons perform approximately 65,000 abdominal aortic aneurysm repairs annually.
However, in a surgical repair procedure called endovascular aneurysm repair, one of every six patients experiences stent-graft leakage from traditional stent-grafts in the month following surgery. Additionally, 20 to 30 percent of patients require additional corrective surgery as much as six to eight years later.
While pursuing her doctoral degree in biomedical engineering at UTSA under the supervision of Agrawal and Bailey, Kaufmann developed a unique scaffold, which promotes tissue formation. The product, called a tissue-engineering scaffold for aneurysm repair (TESAR), creates a tissue barrier between the blood and the aneurysm after it is implanted.
The scaffold promotes healthy tissue formation to repave the aneurysm wall. Once the scaffold is in place, the aneurysm stops expanding and the risk of rupture decreases. After new tissue is in place, the scaffold degrades and is safely reabsorbed by the body.
Cardiovate's TESAR stent-graft has been shown in the laboratory to reduce post-operative complications during aneurysm repair surgery such as the need for additional corrective surgeries following the initial procedure. Also, the natural tissue is a better match for biological healing than the materials found in traditional stent-grafts.
Between now and March 2013, Kaufmann, Agrawal and Bailey will work together to refine the manufacturing of the TESAR, and they will test it to ensure it conforms to the highest safety and quality standards.
"The launch of Cardiovate is testament to the phenomenal technology being created in UTSA labs and the great entrepreneurial ecosystem the university fosters," said Cory Hallam, director of the UTSA Center for Innovation and Technology Entrepreneurship. "These types of spin-offs have the ability to save lives, create jobs, build multi-million-dollar markets and significantly reduce health-care costs caused by complications that arise with the existing technologies."
The scholars expect to make the product available for licensing to a larger company in 2013. Ideally, it then would be on the market for vascular surgeons to use shortly after being evaluated by the FDA.
President Taylor Eighmy is inviting all UTSA faculty and staff to "Tacos With Taylor." Take the opportunity to introduce yourself to the President at any one of these casual meet and greets.
Frio Street Building, Food Court Commons Area, Downtown Campus
Celebrate 40 years of BestFest, an annual event hosted by Roadrunner Productions as a part of UTSA Homecoming festivities. The event will feature a carnival, food and drink booths, a golf cart parade, firework and live music from Anthem.
Brackenridge Lot 1, Main Campus
Celebrate homecoming as the Roadrunners take on Rice. Come early for the Spirit Walk, tailgating, games, music and food. Stick around for a halftime show with SOSA and the crowning of Mr. and Ms. UTSA.
Alamodome, 100 Montana St., Downtown San Antonio
The Leadership Storytelling Homecoming Brunch brings together UTSA alumni and students to share a delicious meal as well as a roundtable conversation about how experiences in college carry us forward on unique leadership journeys.
University Center, Denman Room (UC 2.01.28), Main Campus
The conference is dedicated to sharing recent knowledge and experiences gained in the area of Big Data by researchers in academia, industry and the government sectors within the areas of business, national security, infrastructure, healthcare and visualization. The conference fee is $45 and includes breakfast, lunch & parking. Free for students and non-academic government employees. Register here: https://www.regonline.com/UTSAdataconference2017.
H-E-B University Center Ballroom (HUC 1.104), Main Campus
Former National Security Advisor Susan Rice, via webcast, will examine America’s economic, political and security relations with China during CHINA Town Hall, an 80-city live discussion and Q&A on China and Sino-American relations.
Building Building, Richard Liu Auditorium (BB 2.01.02), Main Campus
The African American Studies program proudly presents William "Cruz" Shaw, San Antonio City Councilman and UTSA Alumnus. Event is free and open to the public.
University Center, Retama Auditorium (UC 2.02.02), Main Campus
The graduate fair is an opportunity for the UTSA student body and local San Antonio community to learn about graduate education opportunities. The event is free and open to the public.
H-E-B University Center Ballroom (1.104), Main Campus
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