(May 23, 2012) ---University of Texas at San Antonio (UTSA) alumna Jordan Kaufmann, Ph.D.; UTSA College of Engineering Dean Mauli Agrawal; and UT Medicine San Antonio cardiologist Steven Bailey, M.D., have launched Cardiovate, a technology start-up that will offer a new and much-needed cardiovascular stent-graft to prevent aneurysm leakage following cardiovascular surgeries.
Kaufmann, an alumna of the UTSA College of Engineering's Department of Biomedical Engineering, developed the stent-graft as part of her doctoral research with UTSA's Agrawal and Bailey, division chief for cardiology in the School of Medicine of the UT Health Science Center San Antonio.
"To take an idea that we were throwing around and develop it all the way to a product for a start-up company has been an incredible opportunity," said Kaufmann. "The path epitomized both translational research and multidisciplinary studies, which has been a great educational experience."
Approximately 1.2 million people in the United States suffer from an abdominal aortic aneurysm. Aneurysm rupture is the nation's 13th leading cause of death. Surgeons perform approximately 65,000 abdominal aortic aneurysm repairs annually.
However, in a surgical repair procedure called endovascular aneurysm repair, one of every six patients experiences stent-graft leakage from traditional stent-grafts in the month following surgery. Additionally, 20 to 30 percent of patients require additional corrective surgery as much as six to eight years later.
While pursuing her doctoral degree in biomedical engineering at UTSA under the supervision of Agrawal and Bailey, Kaufmann developed a unique scaffold, which promotes tissue formation. The product, called a tissue-engineering scaffold for aneurysm repair (TESAR), creates a tissue barrier between the blood and the aneurysm after it is implanted.
The scaffold promotes healthy tissue formation to repave the aneurysm wall. Once the scaffold is in place, the aneurysm stops expanding and the risk of rupture decreases. After new tissue is in place, the scaffold degrades and is safely reabsorbed by the body.
Cardiovate's TESAR stent-graft has been shown in the laboratory to reduce post-operative complications during aneurysm repair surgery such as the need for additional corrective surgeries following the initial procedure. Also, the natural tissue is a better match for biological healing than the materials found in traditional stent-grafts.
Between now and March 2013, Kaufmann, Agrawal and Bailey will work together to refine the manufacturing of the TESAR, and they will test it to ensure it conforms to the highest safety and quality standards.
"The launch of Cardiovate is testament to the phenomenal technology being created in UTSA labs and the great entrepreneurial ecosystem the university fosters," said Cory Hallam, director of the UTSA Center for Innovation and Technology Entrepreneurship. "These types of spin-offs have the ability to save lives, create jobs, build multi-million-dollar markets and significantly reduce health-care costs caused by complications that arise with the existing technologies."
The scholars expect to make the product available for licensing to a larger company in 2013. Ideally, it then would be on the market for vascular surgeons to use shortly after being evaluated by the FDA.
The CACP 2016-2017 Speaker Series continues with architect and writer Jason Griffiths of the University of Arizona and Jason Griffiths Architecture. His practice is based on a multidisciplinary approach.
Buena Vista Building, Aula Canaria Auditorium (BVB 1.328), Downtown Campus
UTSA's Department of Music hosts Dr. David Huron from Ohio State University as part of the Donald Hodges lecture series. Huron is a Canadian arts and humanities distinguished professor at Ohio State University.
John Peace Library, UTSA Faculty Center, (JPL 4.04.22), Main Campus
The UTSA community is encouraged to donate blood and save a life. Donors will also receive a free t-shirt.
H-E-B University Center parking lot, Main Campus
Dr. Stephanie Westney (violin) presents a concert of Mozart compositions as performed by herself and other talented musicians from the university and surrounding area. This concert is free and open to the public.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The Student Center for Community Engagement and Inclusion annually hosts a Volunteer Opportunities Fair to allow students, faculty and staff to learn about volunteer and service-learning opportunities in the San Antonio area.
University Center, 1st floor corridor, Main Campus
Join the conversation about the experiences of military-connected families in transition. Free parking in the Cattleman Square (along Buena Vista Street). The event is free and open to the public.
Frio Street Building, Riklin Auditorium (FS 1.406), Downtown Campus
School district superintendents and other district leaders responsible for bilingual and ESL programs' administration and accountability learn about cultural literacy, language, and diversity in the community.
Recruiters from across the STEM fields will be present with full-time, part-time and/or internship opportunities. Dress professional and bring plenty of resumes.
Convocation Center, Main Campus
Recruiters from across all fields looking to hire students with all different majors will be present at this event looking to hire for their full-time and/or internship opportunities. Professional dress is required. Bring plenty of resumes.
Convocation Center, Main Campus
The Civic Engagement Summit is an opportunity to celebrate and showcase UTSA's commitment to civic engagement through a myriad of efforts by students, faculty and staff, highlighting the significant ways the university impacts the local community.
H-E-B University Center Ballroom, (HUC 1.104), Main Campus
The Department of Demography presents Dr. Rodolfo Cruz Peñeiro of El Colegio de la Frontera Norte. His presentation is titled "Changes in the Migratory Dynamics of the Northern Mexican Border." This event is free and open to the public.
Monterrey Bldg., (MNT 3.240), UTSA Downtown Campus
Grab your friends, family, kids and dog for this annual fun run on the UTSA Main Campus benefititng the UTSA Alumni Association.
Convocation Center, Main Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
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