(May 23, 2012) ---University of Texas at San Antonio (UTSA) alumna Jordan Kaufmann, Ph.D.; UTSA College of Engineering Dean Mauli Agrawal; and UT Medicine San Antonio cardiologist Steven Bailey, M.D., have launched Cardiovate, a technology start-up that will offer a new and much-needed cardiovascular stent-graft to prevent aneurysm leakage following cardiovascular surgeries.
Kaufmann, an alumna of the UTSA College of Engineering's Department of Biomedical Engineering, developed the stent-graft as part of her doctoral research with UTSA's Agrawal and Bailey, division chief for cardiology in the School of Medicine of the UT Health Science Center San Antonio.
"To take an idea that we were throwing around and develop it all the way to a product for a start-up company has been an incredible opportunity," said Kaufmann. "The path epitomized both translational research and multidisciplinary studies, which has been a great educational experience."
Approximately 1.2 million people in the United States suffer from an abdominal aortic aneurysm. Aneurysm rupture is the nation's 13th leading cause of death. Surgeons perform approximately 65,000 abdominal aortic aneurysm repairs annually.
However, in a surgical repair procedure called endovascular aneurysm repair, one of every six patients experiences stent-graft leakage from traditional stent-grafts in the month following surgery. Additionally, 20 to 30 percent of patients require additional corrective surgery as much as six to eight years later.
While pursuing her doctoral degree in biomedical engineering at UTSA under the supervision of Agrawal and Bailey, Kaufmann developed a unique scaffold, which promotes tissue formation. The product, called a tissue-engineering scaffold for aneurysm repair (TESAR), creates a tissue barrier between the blood and the aneurysm after it is implanted.
The scaffold promotes healthy tissue formation to repave the aneurysm wall. Once the scaffold is in place, the aneurysm stops expanding and the risk of rupture decreases. After new tissue is in place, the scaffold degrades and is safely reabsorbed by the body.
Cardiovate's TESAR stent-graft has been shown in the laboratory to reduce post-operative complications during aneurysm repair surgery such as the need for additional corrective surgeries following the initial procedure. Also, the natural tissue is a better match for biological healing than the materials found in traditional stent-grafts.
Between now and March 2013, Kaufmann, Agrawal and Bailey will work together to refine the manufacturing of the TESAR, and they will test it to ensure it conforms to the highest safety and quality standards.
"The launch of Cardiovate is testament to the phenomenal technology being created in UTSA labs and the great entrepreneurial ecosystem the university fosters," said Cory Hallam, director of the UTSA Center for Innovation and Technology Entrepreneurship. "These types of spin-offs have the ability to save lives, create jobs, build multi-million-dollar markets and significantly reduce health-care costs caused by complications that arise with the existing technologies."
The scholars expect to make the product available for licensing to a larger company in 2013. Ideally, it then would be on the market for vascular surgeons to use shortly after being evaluated by the FDA.
The winners of the competition held in December perform instrumental concertos and selections from operas accompanied by the orchestra. Tickets are $5. Each UTSA student with ID get one free ticket.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The College of Engineering invites you to the Tech Symposium showcasing innovative student projects & research performed across multiple disciplines. The symposium will not only include work in engineering, but also advances achieved in business and science.
Convocation Center, Main Campus
The Historical Trumpets and Flutes are premier chamber ensembles within the US Army Old Guard Fife and Drum Corps. actively serving their community and official military ceremonies will perform at UTSA. The concert is free and open to the public.
Arts Building, Band Rehearsal Hall (ARTS 2.03.20), Main Campus
Please join us for a free research symposium of nationally renowned scholars who will share their insights on 21st century educational policies and the climate they foster for today's schools, teachers and students.
Durango Building, Southwest Room (DB 1.124), Downtown Campus
The unofficial Fiesta event is an alcohol-free party that's a favorite among the UTSA community and San Antonio families. There will be free food, live music and other activities. Students will also be able to test out texting and driving and drunk driving simulators.
Paseo, Main Campus
United to Serve is a System-wide volunteer initiative involving UT System students, administrators, faculty and staff. Join fellow Roadrunner volunteers for this kickoff event prior to volunteering.
University Center Lawn, Main Campus
UTSA Music Biz Day is an annual music symposium for the San Antonio community and students to network with music professionals and learn about how to get involved in the industry independent of experience. The event is free and open to all.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
The Policy Studies Center is hosting its first statewide Latino Policy Symposium to address public policies that contribute to the well-being of Latino families. The theme is Path to Power and Prosperity. This working summit provides an opportunity for public agencies, non-profits to review the impact of local and state policies targeting education, labor/employment/housing, and health and human services.
Buena Vista Street Building, Meeting Assembly Room (BVB 1.338), Downtown Campus
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
To be a premier public research university, providing access to educational excellence and preparing citizen leaders for the global environment.
We encourage an environment of dialogue and discovery, where integrity, excellence, inclusiveness, respect, collaboration and innovation are fostered.