(Dec. 13, 2012) -- UTSA graduate students Christine Lindsay Miller and Aimee Signarovitz and post-doctoral fellow Rishein Gupta were recognized for outstanding research poster presentations at the inaugural San Antonio Vaccine Development Center (SAVE) Symposium. The symposium, "Vaccine Antigen Discovery and Vaccine-Induced Immunity," was held Nov. 16 at the UT Health Science Center San Antonio Greehey Children's Cancer Research Institute.
Miller, Gupta and Signarovitz are all conducting research in the College of Sciences Department of Biology. They received the first, second and third prize, respectively, for their symposium presentations.
Antigens are substances such as bacteria, fungi or pollen that stimulate the immune system to produce antibodies. An antibody is a protein produced by the immune defenses when the harmful antigen is recognized.
Under the direction of Janakiram Seshu, associate professor of microbiology, UTSA cell and molecular biology doctoral student Christine Miller is studying Borrelia burgdorferi, the bacterium that causes Lyme disease. The bacterium is carried by ticks and expresses proteins that allow it to quickly adapt to its mammalian host and cause disease.
Scientists have identified the gene expression regulators that allow B. burgdorferi to express the proteins it needs to survive. Miller, however, has found a regulator that turns the genes off, a critical piece of information for the development of a vaccine against Lyme disease. Her poster, "Role of Borrelia burgdorferi Host-Adaptation Regulator (BadR) in the Patho-physiology of the Agent of Lyme Disease," presented her findings.
In 2009, Gupta joined UTSA professor Bernard Arulanandam's laboratory as a post-doctoral researcher to study host immune responses against chlamydial infections and effective intervention techniques. The bacterium Chlamydia trachomatis is one of the leading causes of sexually transmitted diseases.
Gupta's poster, "In Vivo Whole Animal Body Imaging Reveals the Possible Contribution of Host Innate Factors in Early Colonization of Chlamydia trachomatis Within the Murine Female Genital Tract," demonstrated how to track fluorescent stained bacteria and monitor their movement inside the body in real-time. He is especially interested in understanding how a hosts immune system may aid the progression of the infection and how to inhibit those processes to develop a vaccine that prevents the infection from spreading.
Signarovitz is a UT Health Science Center student pursuing her doctoral degree in microbiology and immunology. Like Gupta, she researches in Arulanandam's laboratory. Her poster, "Mucosal Immunity from Oral Vaccination Involves Antigen Trafficking By M-cells and Goblet Cells," explores two types of cells involved in oral vaccinations. M-cells are known to remove antigens from intestines. Goblet cells make mucus in intestines and lungs. Using the bacterium Francisella tularensis, which causes the disease tularemia, she is researching ways to affect the body's immune response during vaccination.
The San Antonio Vaccine Development Center, launched in 2012 with assistance from BioMed SA, builds upon the mutual vaccine research resources of four San Antonio institutions: UTSA, UT Health Science Center, Texas Biomedical Research Institute and Southwest Research Institute. This month's symposium was the center's inaugural event.
"We were so pleased to see posters presentations of such a high quality at our inaugural symposium," said Bernard Arulanandam, the UTSA Jane and Roland Blumberg Professor of Biology. "Our UTSA students fared very well in a competitive arena. We are so proud of their hard work and the opportunity the symposium gave them to learn about infectious disease research programs beyond their own areas."
Muralist Crystal Arias will discuss her current mural "Cultivate the Past to Prestige" at La India Herbs and themes she utilizes in her other works.
McKinney Humanities Building (MH 3.02.26), Main Campus
The UTSA Department of Modern Languages and Literatures is a co-sponsor of the CARTA 19th Annual Conference. The group meets annually to exchange educational programs, ideas, and techniques and to network with other teachers of Russian. Registration required.
DoubleTree by Hilton, Downtown San Antonio
Into the Woods is a musically sophisticated show with a leaning towards dark comedy. Dr. William McCrary directs. $15 tickets $10 students military seniors 55+ with IDs $8 groups of ten or more in any price level. There will be a second show Sunday, April 2 at 3 p.m.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
UTSA faculty, staff and students are members of the Helotes Area Community Band and are proud to present a special Tapestry of Concert Band Classics. The event is free and open to the community.
John Marshall High School Auditorium, 8000 Lobo Lane, San Antonio
A record number of candidates are running for the San Antonio City Council's District 5 seat. Come hear what they have to say. Event hosted by the UTSA College of Public Policy and League of Women Voters, in partnership with PASO and Alpha Phi Sigma.
Buena Vista Street Building, Aula Canaria (BVB 1.328), Downtown Campus
The former EPA Chief Statistician and current ASA president, Dr. Barry Nussbaum will talk about how statistics can make a big difference in influencing decisions and actions. Example include the court cases and material presented to the US president.
John Peace Library, Assembly Room (JPL 4.04.22), Main Campus
The UTSA African American Studies Program invites everyone to hear guest speaker Dr. Elaine Richardson, professor of literacy studies at The Ohio State University.
Durango Building, Southwest Room (DB 1.124), Downtown Campus
Join the Department of Kinesiology, Health, and Nutrition for a free lecture on molecular maps for physical activity presented by Dr. Blake Rasmussen, professor from the University of Texas Health Science Center, Medical Branch.
John Peace Library, Assembly Room (JPL 4.04.22), Main Campus
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