(June 17, 2013) --University of Texas at San Antonio biomedical engineering Ph.D. candidate Anand Srinivasan has been awarded a $25,000, one-year doctoral fellowship from the American Heart Association (AHA). This highly competitive fellowship provides significant funding to doctoral students to support research and training in cardiovascular and stroke discoveries.
For nearly four years, Srinivasan has developed and tested a series of prototype nanochips under the guidance of UTSA biomedical engineering assistant professor Anand Ramasubramanian and biology professor Jose Lopez-Ribot in collaboration with the director of science at the U.S. Institute of Surgical Research, Kai P. Leung. Their nanochips aid in high-throughput screening, an automated process that allows researchers to quickly test small molecules against an array of thousands of microbial biofilms.
Supported by the AHA, Srinivasan will develop a new chip-based platform that can be used to test the effectiveness of drug treatments for infective endocarditis, a dangerous bacterial-fungal infection of the heart's inner lining. The research is a challenge because it requires Srinivasan to develop a chip that will facilitate bacterial and fungal co-culture biofilms at a nano scale.
Infective endocarditis is an example of a health care-associated infection (HAI), devastating and even deadly infections caused by microorganisms such as bacteria and fungus. Patients generally acquire HAIs when they receive treatment for other conditions, often as a result of their compromised immune systems. According to the Centers for Disease Control and Prevention, approximately one of every 20 hospitalized patients will contract an HAI.
While the medical community is fighting back against HAIs by testing thousands of microbial biofilm samples from hospital surfaces throughout the world, the process is time consuming and costly. The technology currently in use also is outdated.
"The industry standard process currently in place was developed back in the 1950s and tests only a few hundred samples at a time," said Srinivasan. "Using chip-based, high-throughput technology, we have developed a process that is quicker and cheaper. Just one of our nanochips can test 1,200 samples simultaneously."
"We are fortunate to have Anand work on this project," said Ramasubramanian. "He has shown tremendous dedication, resolve and passion all along in integrating microbiology into chip design and fabrication, which is a big challenge."
Srinivasan has authored seven peer-reviewed journal articles and has been invited to give presentations on his discoveries at several conferences across the country, including the American Society of Microbiology and Biomedical Engineering Society. Most recently, his paper, "A High-Throughput Nano-Biofilm Microarray for Antifungal Drug Discovery," was accepted by mBio, the peer-reviewed journal of the American Society for Microbiology, and was published this month.>> Learn more about the UTSA Department of Biomedical Engineering.
President Taylor Eighmy is inviting all UTSA faculty and staff to "Tacos With Taylor." Take the opportunity to introduce yourself to the President at any one of these casual meet and greets.
Frio Street Building, Food Court Commons Area, Downtown Campus
Celebrate 40 years of BestFest, an annual event hosted by Roadrunner Productions as a part of UTSA Homecoming festivities. The event will feature a carnival, food and drink booths, a golf cart parade, firework and live music from Anthem.
Brackenridge Lot 1, Main Campus
Celebrate homecoming as the Roadrunners take on Rice. Come early for the Spirit Walk, tailgating, games, music and food. Stick around for a halftime show with SOSA and the crowning of Mr. and Ms. UTSA.
Alamodome, 100 Montana St., Downtown San Antonio
The Leadership Storytelling Homecoming Brunch brings together UTSA alumni and students to share a delicious meal as well as a roundtable conversation about how experiences in college carry us forward on unique leadership journeys.
University Center, Denman Room (UC 2.01.28), Main Campus
The conference is dedicated to sharing recent knowledge and experiences gained in the area of Big Data by researchers in academia, industry and the government sectors within the areas of business, national security, infrastructure, healthcare and visualization.
H-E-B University Center Ballroom (HUC 1.104), Main Campus
Former National Security Advisor Susan Rice, via webcast, will examine America’s economic, political and security relations with China during CHINA Town Hall, an 80-city live discussion and Q&A on China and Sino-American relations.
Building Building, Richard Liu Auditorium (BB 2.01.02), Main Campus
The African American Studies program proudly presents William "Cruz" Shaw, San Antonio City Councilman and UTSA Alumnus. Event is free and open to the public.
University Center, Retama Auditorium (UC 2.02.02), Main Campus
The graduate fair is an opportunity for the UTSA student body and local San Antonio community to learn about graduate education opportunities. The event is free and open to the public.
H-E-B University Center Ballroom (1.104), Main Campus
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