(July 16, 2013) -- Researchers at The University of Texas at San Antonio and Southwest Research Institute (SwRI) jointly announce they are investing $200,000 in new research aimed at developing a synthetic drug-loaded scaffold to use in bone grafting procedures.
More than three million musculoskeletal procedures are currently performed in the United States each year to repair bone tissue damage from trauma, congenital deformities, bone diseases and the removal of cancerous lesions.
The UTSA-SwRI bone graft substitute would be an improvement on the industry's gold standard, autologous grafting. Autologous grafting, the process of transferring bone grafts from one part of the body to another, is generally successful in particular types of bone grafting. However, challenges arise due to tissue scarcity and surgical complications. Additionally, autologous grafts are not effective in treating large bone defects.
UTSA and SwRI researchers Anson Ong, the USAA Foundation Distinguished Professor in Biomedical Engineering, and Jian Ling, staff engineer at SwRI, will use collagen and hydroxyapatite to create their synthetic scaffold. Natural bone is, in large part, made up of collagen, hydroxyapatite and water.
Their proposed scaffold would have a rigid structural framework with complementary elastic properties, making it an ideal bone substitute to endure the body's tough physiological demands. Additionally, the synthetic bone substitute would be scalable. Clinicians would be able to trim it into any shape to fit large bone defects.
Ong and Ling's unique scaffold also would include drug-microparticles. Those microparticles would release active growth factors in a controlled manner over time, causing stem cells to become bone cells to which the implanted scaffold would fuse.
If successful, the new product would tap the unmet needs of an annual $2.5 billion bone graft market.
Ling has more than 19 years of experience in biomedical research, including the development of collagen- hydroxyapatite composite scaffolds. Ong is an established expert in the field of bone-biomaterial tissue interfaces.
The Connect Program, an annual UTSA-SwRI joint funding initiative, was established in 2010 to stimulate inter-organizations research between UTSA scholars and SwRI investigators in fields such as advanced materials, chemistry and chemical engineering, energy, the environment, security and manufacturing.
The College of Engineering invites you to the Tech Symposium showcasing innovative student projects & research performed across multiple disciplines. The symposium will not only include work in engineering, but also advances achieved in business and science.
Convocation Center, Main Campus
The Historical Trumpets and Flutes are premier chamber ensembles within the US Army Old Guard Fife and Drum Corps. actively serving their community and official military ceremonies will perform at UTSA. The concert is free and open to the public.
Arts Building, Band Rehearsal Hall (ARTS 2.03.20), Main Campus
Free presentation: Join us as we take a virtual tour of La Provence led by Claudia Carvalho. You will have an opportunity to immerse yourself in France and French culture by experiencing it from a touristical and cultural perspective.
McKinney Humanities (MH 2.01.04), Main Campus
Please join us for a free research symposium of nationally renowned scholars who will share their insights on 21st century educational policies and the climate they foster for today's schools, teachers and students.
Durango Building, Southwest Room (DB 1.124), Downtown Campus
The unofficial Fiesta event is an alcohol-free party that's a favorite among the UTSA community and San Antonio families. There will be free food, live music and other activities. Students will also be able to test out texting and driving and drunk driving simulators.
Paseo, Main Campus
United to Serve is a System-wide volunteer initiative involving UT System students, administrators, faculty and staff. Join fellow Roadrunner volunteers for this kickoff event prior to volunteering.
University Center Lawn, Main Campus
This session will cover Texas' high school graduation requirements and more. It is geared toward parents and families of middle school students planning for high school entry and students already in high school considering going to college.
Buena Vista Street Building, Aula Canaria Auditorium (BVB 1.328), Downtown Campus
UTSA Music Biz Day is an annual music symposium for the San Antonio community and students to network with music professionals and learn about how to get involved in the industry independent of experience. The event is free and open to all.
Arts Building, Recital Hall (ARTS 2.03.02), Main Campus
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