(July 16, 2013) -- Researchers at The University of Texas at San Antonio and Southwest Research Institute (SwRI) jointly announce they are investing $200,000 in new research aimed at developing a synthetic drug-loaded scaffold to use in bone grafting procedures.
More than three million musculoskeletal procedures are currently performed in the United States each year to repair bone tissue damage from trauma, congenital deformities, bone diseases and the removal of cancerous lesions.
The UTSA-SwRI bone graft substitute would be an improvement on the industry's gold standard, autologous grafting. Autologous grafting, the process of transferring bone grafts from one part of the body to another, is generally successful in particular types of bone grafting. However, challenges arise due to tissue scarcity and surgical complications. Additionally, autologous grafts are not effective in treating large bone defects.
UTSA and SwRI researchers Anson Ong, the USAA Foundation Distinguished Professor in Biomedical Engineering, and Jian Ling, staff engineer at SwRI, will use collagen and hydroxyapatite to create their synthetic scaffold. Natural bone is, in large part, made up of collagen, hydroxyapatite and water.
Their proposed scaffold would have a rigid structural framework with complementary elastic properties, making it an ideal bone substitute to endure the body's tough physiological demands. Additionally, the synthetic bone substitute would be scalable. Clinicians would be able to trim it into any shape to fit large bone defects.
Ong and Ling's unique scaffold also would include drug-microparticles. Those microparticles would release active growth factors in a controlled manner over time, causing stem cells to become bone cells to which the implanted scaffold would fuse.
If successful, the new product would tap the unmet needs of an annual $2.5 billion bone graft market.
Ling has more than 19 years of experience in biomedical research, including the development of collagen- hydroxyapatite composite scaffolds. Ong is an established expert in the field of bone-biomaterial tissue interfaces.
The Connect Program, an annual UTSA-SwRI joint funding initiative, was established in 2010 to stimulate inter-organizations research between UTSA scholars and SwRI investigators in fields such as advanced materials, chemistry and chemical engineering, energy, the environment, security and manufacturing.
Experience a fun, interactive week at UTSA as new students and their families take the first steps to becoming a Roadrunner.
Various locations, Main Campus and Downtown Campuses
Throughout the summer, UTSA offers more than 60 camps in science, engineering, architecture, sports, music, writing, language, culture and more.
Various locations, Main and Downtown Campuses
This event guides seniors and graduate students on the last phase of their college career and prepares recent alumni within one year of graduation for the world of work. Workshops and sessions will provide information on interview skills, job search strategies and networking.
Student Union, University Career Center, 2nd floor, Main Campus
The gala brings together UTSA alumni, friends and guests to celebrate the association's 41 years of scholarships, services, programs and the 2018 Alumni Award recipients.
Hyatt Hill Country Resort and Spa, 9800 Hyatt Resort Dr, San Antonio
As part of the citywide Kidcation and the ITC's free second Sunday, kids and families will have an opportunity to interact with cowboy docents, practice their skills at roping, learn about life on the cattle drives, make their own spurs, grab a seat for cowboy story time and work on cowboy-themed hands-on crafts.
UTSA Institute of Texan Cultures, Hemisfair Campus
Dozens of fun and free events to welcome new and returning Roadrunners.
Various locations, Main and Downtown Campuses
The kickoff to Roadrunner Days, the UTSA community welcomes the thousands of students who move in to their new homes as they begin their journey at UTSA.
Laurel Village, Chaparral Village and Alvarez Hall, Main Campus
After a full day of moving, UTSA students and their families are invited to the party featuring food, swag, dancing and a special performance from the Spirit of San Antonio marching band.
Student Union Paseo, Main Campus
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