UTSA professor creates versatile laser needle for treating cancer
(April 11, 2017) -- Lyle Hood, assistant professor of mechanical engineering at The University of Texas at San Antonio (UTSA), has collaborated with Christopher Rylander, associate professor of mechanical engineering at The University of Texas at Austin, to create a device that can do the work of both a cutting-edge surgical needle and a medical laser. The device has innumerable applications, most notably the ability to eradicate cancerous tumors while also delivering chemotherapy drugs.
Hood originally developed the needle to treat transitional-cell carcinoma, which forms on the interior of the bladder.
"Treating cancer in the bladder is difficult if you want to preserve the organ's ability to hold fluid," he said. "The most typical treatment is to remove the bladder altogether, leaving patients with the need for a urinary bag for the rest of their lives."
To solve this challenge, Hood and Rylander created the laser needle alongside Mehmet Kosoglu, then a graduate student at Virginia Tech. The needle penetrates the tissue to deliver medicine while emitting laser light that kills the tumors without making a hole in the bladder.
He soon discovered that his creation could treat other forms of cancer, including brain cancer, which is challenging to treat for several reasons.
"The problem is that typical chemotherapy for brain cancer involves an IV in the arm, but due to the blood-brain barrier not enough of that concentrated medicine enters the central nervous system and reaches the tumors," Hood said.
Another brain cancer treatment involves dripping chemotherapy into the brain through a catheter inserted through the skull. However, because the brain is a closed fluid environment, too much medicine too quickly can cause overpressure, resulting in more harm than the tumor itself. As a result, not enough medicine reaches the cancer during this treatment. By using the laser needle to slowly heat the tissue during the drip, the chemotherapeutics will disperse much more rapidly and widely.
"I didn't want patients sitting with a catheter in their head for three days, but they obviously need enough chemotherapy to kill the tumor," Hood said. "This solves both problems."
Hood noted that his device can even work in cosmetic surgeries; the laser can melt fat and the needle can remove it.
"If you melt the fat in place, the body just resorbs it, resulting in high levels in the blood," he said. "This is why many existing laser treatments are not very healthy."
For now, Hood is focusing on how his needle can be used to treat other types of cancer, particularly skin cancer.
"The idea is to take the creative approach," he said. "We can go straight in and treat the problem locally without having to circulate chemotherapy."
UTSA is ranked among the top 400 universities in the world and among the top 100 in the nation, according to Times Higher Education.
-------------------------------
Learn more about the UTSA Department of Mechanical Engineering.
Connect with UTSA online at Facebook, Twitter, YouTube, Instagram and LinkedIn.
Events
Learn to use the simple but powerful features of EndNote®, a citation management tool. In this hands-on workshop, participants will learn to setup an EndNote library, save references and PDFs, and automatically create and edit a bibliography.
Virtual EventLearn to use Zotero®, a citation manager that can help you store and organize citations you find during your research. Zotero can generate bibliographies in various styles, insert in-text citations and allow you to share sources with collaborators.
Virtual EventOur GSAW Research Symposium begins with lunch and a Poster Presentation Competition. Faculty, staff, and graduate students are welcome to attend and review the exceptional research from UTSA's best and brightest.
Student Union Ballrooms 1 & 2, Main CampusHear from UTSA doctoral candidate in environmental science, Andre Felton, as he discusses best practices to discuss scholarly research in non-academic settings. Our 2023 Three Minute Thesis (3MT) winners will also share their winning presentations.
Student Union Ballrooms 1 & 2, Main CampusJoin this fun event if you want resume and interview resources, a job or internship, a snow cone from Kona Ice and to socialize.
Sombrilla PlazaIn partnership with San Antonio Metro Health, join us for a special lecture series during Public Health week! An esteemed panel will discuss the job market’s impact on public health departments in Texas municipalities.
Retama Auditorium (SU 2.02.02,) Main CampusThe Task Force for the Shaping the Future of Artificial Intelligence, Cyber, Computing, and Data Science at UTSA initiative will hold a virtual Campus Forum to discuss their findings in Phase I (data gathering). UTSA faculty, staff and students will have an opportunity to ask questions and share ideas before the Task Force moves into Phase II.
Virtual Event