UTSA Alamo CIMA Mentor
Dr. John Zhao
Asymmetric Synthesis of Biologically Active Molecules Using Green Organocatalytic Methods
Since different diastereomers and/or enantiomers of a given molecule may have totally different biological activities, developing novel enantio- and diastereoselective methods for the synthesis of molecules that are of potential biological activities are very important for medicinal chemistry and pharmaceutical industry and for the expansion of their chemical space. Our lab is focused on the application of organocatalysts, which are small organic molecules that can catalyze organic reactions, in the asymmetric synthesis of biologically active molecules/scaffolds. The goal is to achieve a highly efficient and highly stereoselective synthesis of these molecules in a green way. Our lab is equipped with polarimeter and chiral HPLC and GC for the identification and separation of chiral molecules.