Kathryn Mayer, Ph.D.
Lutcher Brown Fellowship
Areas of Specialization
- Optical Techniques
- Single Molecule Studies
Ph.D. in Physics; Rice University
M.S. in Physics; Rice University
B.S. in Physics; Rice University
Our lab uses optical techniques to study the bio-nano interface. In particular, we specialize in the detection and imaging of single molecules, and the interaction of molecules with metal surfaces. We are currently developing three major projects: 1) the use of ultra-sensitive localized surface plasmon resonance (LSPR) sensors to measure molecular binding and conformational changes on surfaces; 2) super-resolution microscopy studies of surface bound molecules, including nanoparticle-bound antibodies; and 3) single-molecule kinetics studies based upon microwell technology. By understanding the details of the bio-nano interface, we hope to improve existing nanoparticle bioconjugate techniques and gain insight into fundamental biophysical questions.