(May 17, 2011)--UTSA researchers Bernard Arulanandam, Jane and Roland Blumberg Professor in Biology and associate dean of research for scientific innovation, and Ashlesh Murthy, research assistant professor in the College of Sciences Department of Biology and South Texas Center for Emerging Infectious Diseases, and researcher Guangming Zhong, professor of microbiology and immunology at the University of Texas Health Science Center at San Antonio (UTHSC), received a U.S. patent based on discoveries the trio made while researching Chlamydia trachomatis, the bacterium that causes chlamydia infections. The patent protects intellectual property related to chlamydia prevention and treatment.
"Doctors Zhong, Murthy and I have been working for many years to better understand the mechanisms of chlamydia infection and to find ways to prevent or treat the disease," said Arulanandam. "When the research was licensed to Merck in 2008 to develop a vaccine, this intellectual property was included."
Chlamydia is among the world's most common sexually transmitted diseases. In the United States alone, it strikes nearly 3 million people annually and is particularly common in those aged 25 years or younger.
Chlamydia is treacherous because it does not always cause symptoms. As a result, many people are unaware they have the disease and do not receive prompt medical treatment. Especially dangerous for women, chlamydia can lead to pelvic inflammatory disease, infertility or potentially fatal ectopic pregnancies.
The researchers have focused their work on the antigen known as chlamydia protease-like activity factor, or CPAF, initially discovered in the Zhong lab. The CPAF protein is made and secreted by the C. trachomatis bacterium.
In 2008, the University of Texas Board of Regents licensed significant portions of Arulanandam, Zhong and Murthy's CPAF-related work to Merck. The licensing agreement was facilitated by South Texas Technology Management, a regional technology transfer office that supports commercialization activities at the UTHSC, UTSA, University of Texas-Pan American and University of Texas at Brownsville.
Zhong has conducted research for more than 25 years in chlamydia pathogenesis and vaccine development, while Arulanandam has researched vaccine development and mucosal immunity for nearly 15 years. Murthy joined the team in 2001 as the first student in UTSA's doctoral degree program in cellular and molecular biology. He graduated from the program in 2006 and continues to research chlamydia in Arulanandam's UTSA laboratory.
"We are very pleased with this patent," said Murthy. "Ultimately, that is why we are conducting this research. We want to improve public health. We want to turn the tables on this disease."
About the University of Texas Health Science Center at San Antonio
The University of Texas Health Science Center at San Antonio, one of the country's leading health sciences universities, ranks in the top 3 percent of all institutions worldwide receiving federal funding. Research and other sponsored program activity totaled $228 million in fiscal year 2010. The university's schools of medicine, nursing, dentistry, health professions and graduate biomedical sciences have produced approximately 26,000 graduates. The $744 million operating budget supports eight campuses in San Antonio, Laredo, Harlingen and Edinburg.
The University of Texas at San Antonio is one of the fastest growing higher education institutions in Texas and the third largest of nine academic universities and six health institutions in the UT System. As a multicultural institution of access and excellence, UTSA aims to be a national research university providing access to educational excellence and preparing citizen leaders for the global environment. UTSA serves more than 30,000 students in more than 130 degree programs in the colleges of architecture, business, education and human development, engineering, honors, liberal and fine arts, public policy, and sciences, and the graduate school. Founded in 1969, UTSA is an intellectual and creative resource center and a socioeconomic development catalyst for Texas and beyond.
About South Texas Technology Management
STTM is the UT technology transfer office serving UTHSC, UTSA and other institutions in the South Texas region. STTM provides leadership in promoting innovation and technology transfer through proactive management of IP, technology development and commercialization to support the missions of member institutions, advance regional economic development and benefit the public. Learn more about STTM and other innovative UT technologies.
The UTSA community is invited to attend the 3rd annual Rowdy Gras celebration! This year Rowdy Gras includes a daytime event from 11 a.m. -1 p.m. with a free food tasting and music on the UC Paseo. The main event takes place from 6 - 9 p.m. in the UC Lawn. The event includes free food, live jazz music, activities and giveaways.
University Center Paseo & Lawn, UTSA Main Campus
The UTSA College of Architecture, Construction and Planning’s 2015-16 Speaker Series continues with Dana Cuff, Ph.D., a professor of architecture and urbanism at the University of California, Los Angeles. In her talk, Cuff will discuss new forms of “studio” and new types of practices. Free and open to the public.
Aula Canaria Lecture Hall (BV 1.328), UTSA Downtown Campus
The UTSA Institute of Texan Cultures invites Texas and Texans to the Asian Festival. What began as a traditional family reunion for the Chinese New Year has expanded to include other Asian communities and participants, showcasing their unique culture and traditions.
The UTSA Institute of Texan Cultures
Join the UTSA Department of Interdisciplinary Learning and Teaching in celebrating interdisciplinary inquiry at the 2016 Interdisciplinary Studies Colloquium. The colloquium will include a panel of faculty and recent doctoral graduate and a showcase of the best IDS undergraduate inquiry projects of the year 2015. The event is free and open to the public.
Business Building (BB 2.06.04), UTSA Main Campus
The UTSA College of Architecture, Construction and Planning (CACP) welcomes renowned architect Cesar Pelli as part of the CACP’s 2015-16 Speaker Series. Pelli is founder and Senior Principal of the New Haven, Conn. firm Pelli Clarke Pelli Architects. In his talk, “Becoming an Architect,” Pelli will present and discuss projects that were critical steps in his career.
Buena Vista Theater (BV 1.326), Downtown Campus
The UTSA College of Public Policy presents the Dean's Distinguished Lecture Series featuring Dr. Iris Carlton-LaNey, Professor of the School of Social Work at the University of North Carolina-Chapel Hill. Dr. Iris Carlton LaNey will speak to the UTSA community about the role and impact of African-Americans in the social work profession.
Buena Vista Theater (BV 1.326), Downtown Campus
The UTSA College of Public Policy presents the Dean's Distinguished Lecture Series featuring Dr. Iris Carlton-LaNey, Professor of the School of Social Work at the University of North Carolina-Chapel Hill. Dr. Carlton-LaNey will speak to the UTSA community about the role and impact of African-Americans in the social work profession.
Buena Vista Theater (BV 1.326), Downtown Campus
Please join us for a presentation and book signing by Luis Carlos Montalván (Fmr. Capt., USA), author of the New York Times Bestseller Until Tuesday and the international award-winning childrens book Tuesday Tucks Me In. His books will be available for purchase at the UTSA Bookstore. This event is free and open to the public.
Southwest Room (DB 1.124), Downtown Campus
The 12th Annual Black Heritage Gala is a formal event which includes a student performance, keynote remarks by Michael Brown, an award presentation, dinner and dancing. Tickets are $10 for UTSA students and $15 for all other guests. Tickets are on sale now at Roadrunner Express. Contact (210) 458-4770 for more information.
H-E-B University Center Ballroom, Main Campus
The UTSA Institute of Texan Cultures will host a free workshop focusing on teaching Latin American culture and geography for students seeking their teacher certification. The workshop includes free resources for teaching Latin American subject matter as well as presentations on language, identity, music, geography, and political and developmental history, and a special educators’ tour of the museum’s Los Tejanos exhibit. Free with registration.
The UTSA Institute of Texan Cultures (ITC 3.01.02)
Faithful Alabi holds the Raw Teen III American deadlift record
2015 was a significant year for UTSA. As the university moved forward on the road to Tier One research, designations and recruitment of high caliber faculty and students, it also completed its first ever capital campaign. Read about UTSA's accomplishments in the 2015 Year in Review as we look forward to what the next year will bring.
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
To be a premier public research university, providing access to educational excellence and preparing citizen leaders for the global environment.
We encourage an environment of dialogue and discovery, where integrity, excellence, inclusiveness, respect, collaboration and innovation are fostered.