George Perry, Ph.D.
Semmes Foundation Distinguished University Chair in Neurobiology
Ph.D. in Marine Biology; Scripps Institution of Oceanography
B.A. in Zoology; University of California, Santa Barbara
Dr. Perry's studies are focused on the mechanism of formation and physiological consequences of the cytopathology of Alzheimer disease. The lab has shown that oxidative damage is the initial cytopathology in Alzheimer disease. They are working to determine the sequence of events leading to neuronal oxidative damage and the source of the increased oxygen radicals. Current studies focus on the:
- Role of redox active metals in mediating prooxidant and antioxidant properties
- Mechanism of phosphorylation control of oxidative damage to neurofilament proteins
- Mass spectrometry analysis of protein metal binding and crosslinking