Lacy Barton, Ph.D.
Areas of Specialization
- Cell Signaling and Migration
- Ovary and Testis Development
- Primordial Germ Cell Dynamics
- Reproductive Developmental Biology
Ph.D in Biochemistry; University of Iowa
B.S. in Biochemistry; University of Wisconsin-La Crosse
A.A.; University of Wisconsin-Baraboo/Sauk Country
Establishment and protection of the germline is critical to fertility and health of the next generation. Our research mission is to understand how the germline accomplishes this important function.
Our research group explores the developmental underpinnings of fertility in early embryogenesis. We are particularly interested in a widely conserved stage when the embryonic germ cells migrate through several tissues to colonize the somatic gonad, while simultaneously undergoing many other developmental processes, including sex-specific differentiation, cell division, and population pruning. Our current focus is to understand how these processes are spatially and temporally coordinated by the surrounding soma and developing ovary and testis.
We combine Drosophila genetics with fixed and live whole animal imaging, in vitro migration assays, and a diverse array of cell and molecular biology approaches to discover new factors and unravel complex cell-cell interactions required for reproductive development. We then test the conservation of our discoveries in the mouse model to reveal deeply conserved reproductive development biology.
We are recruiting at all levels! Our diverse research projects and commitment to a supportive and inclusive environment is well-suited for undergraduates, graduates, and postgraduates. Moreover, bolstering diversity, retention, and resilience during STEM career development is integral to our mission. If you are interested in joining our team, please send your resume/CV and cover letter to Lacy.Barton@utsa.edu.
For more information, stay tuned to www.germline.dev.