(Sept. 25, 2017) -- Jing Yong Ye, professor of biomedical engineering at The University of Texas at San Antonio (UTSA), has received a two-year, $354,617 grant from the National Institutes of Health’s National Cancer Institute to support the development of his noninvasive method of detecting prostate cancer.
Ye’s research team has been working on the development of a novel microscope based on a photonic crystal biosensor to detect the cancer through a urine sample. It will significantly improve accuracy compared to the approach used in current clinical practice.
Prostate cancer is the second most prevalent type of cancer, and the third leading cause of cancer-related deaths, in men. Early detection is key to survival, which is why doctors are required to screen all men over the age of 50 for the disease.
To screen patients for prostate cancer, medical professionals take a blood sample and look for prostate-specific antigen (PSA). If a high level of PSA is found, the patient is suspected to have prostate cancer and required to have a prostate biopsy.
Unfortunately, PSA tests are far from providing satisfactory diagnoses and result in a large number of unnecessary prostate biopsies due to a high false-positive rate. This is because PSA elevation may also occur in men with infection and chronic inflammation or benign prostatic hyperplasia.
“False positive diagnoses are very common in prostate cancer tests,” Ye said. “As a result, a patient may undergo a biopsy he doesn’t need, which is painful and could cause an infection. Also, because prostate cancer is highly heterogeneous and even multicore prostate biopsy only samples a few local areas, it can easily be missed by clinicians.”
Since about 70 percent of men who go through the biopsy process are found to be cancer-free, Ye wanted to look for a better way. His research team will develop a noninvasive imaging approach to check urine samples, since cells from the prostate are shed into urine naturally.
“The system we are developing utilizes a sensitive biosensor, which allows us to distinguish cancer cells from normal cells based on a unique feature of the cells,” he said. “If you can detect a cancer cell, you’re starting from a more precise place and you can give a more accurate diagnosis.”
Ye’s laboratory develops cutting edge tools based on different biosensors, optical imaging methods and nanobiotechnology to address critical issues in biomedical engineering research and applications.
“We need to use every weapon in our arsenal to attack this disease,” Ye said. “It’s important to think outside the box and use innovation to address these critical issues.”
UTSA is recognized as one of the top five young universities in the nation by Times Higher Education.
A UTSA tradition since Homecoming 2011 with Fraternity and Sorority Life, thiscampus-wide talent show showcases the Rowdy Roadrunner Spirit, from teams to individual acts. Everyone will compete to win the 2017 Roadrunners LIVE Champion title.H-E-B University Center Ballrooms (HUC 1.104 and HUC 1.106), Main Campus
Join Rowdy Crew near the Roadrunner Statue for food, games and information to get hyped for the game. Some UTSA football players also plan to stop by.Central Plaza, Main Campus
Interested in becoming a dietitian? Come and speak to our faculty! Bring questions, hear them speak, and obtain information. Event is free.Main Building (MB 2.220), Main Campus
Be ready to laughs during this entertaining evening at the Homecoming Comedy Show! Free with a UTSA Student ID.H-E-B University Center Ballrooms (HUC 1.104 and HUC 1.106), Main Campus
Organizations participating in the golf cart parade will be creatively decorating their carts in the 2017 UTSA Homecoming theme "Spirit, Tradition, and Pride".University Center Lawn, Main Campus
As he wrote about in his book, Kill It To Save It: An Autopsy of Capitalism's Triumph Over Democracy, Corey Dolgon will speak about what made Donald Trump the preferred choice for many voters and shows how policy is crafted, marketed and sold or rejected.Buena Vista Street Building, Aula Canaria Lecture Hall (BVB 1.328), Downtown Campus
The UTSA African American Studies Program is proud to present Dr. Rupert Evans, a Harvard Macy Scholar and the immediate past President of the Institute for Diversity in Health Management.Main Building (MB 0.208), Main Campus
President Taylor Eighmy is inviting all UTSA faculty and staff to "Tacos With Taylor." Take the opportunity to introduce yourself to the President at any one of these casual meet and greets.Frio Street Building, Food Court Commons Area, Downtown Campus
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