SEPTEMBER 24, 2020 — The Cancer Prevention and Research Institute of Texas has awarded UTSA professor Hyoung-gon Lee $250,000. The two-year grant will fund Lee’s research, which seeks to understand the pathogenic mechanism of peripheral neuropathy and to develop a novel therapeutic approach.
“Chemotherapy-induced peripheral neuropathy is a devastating consequence of cancer treatment regimens that include neurotoxic chemotherapeutic agents such as cisplatin,” said Lee, who is an associate professor in the Department of Biology, housed in UTSA’s College of Sciences. Lee is also a member of UTSA’s Brain Health Consortium.
“CIPN is one of the most common, serious side effects that can lead to dose reductions or early discontinuation of chemotherapy, reducing the efficacy of cancer treatments and significantly impacts the quality of life of the patients due to debilitating neurological symptoms such as pain, tingling sensation, numbness and weakness.”
Despite the high prevalence and severity of CIPN, there is currently not an effective treatment to prevent or reverse CIPN. This is mainly due to the scientific community’s limited understanding of the pathogenic mechanism of CIPN. The development of therapeutics is required to improve quality of life in cancer patients and survivors as well as enhance the therapeutic effectiveness of chemotherapy.
“Based on the previous studies, we developed a hypothesis that the induction of cell cycle activity in dorsal root ganglion sensory neurons, the main cell type affected by chemotherapeutic agents, is a key mechanism causing neurotoxicity in cisplatin-induced CIPN and thus targeting this mechanism may provide an effective therapeutic opportunity,” Lee said.
As a part of its continued commitment to cancer research in Texas, CPRIT awarded 62 new grants totaling over $114 million and consisting of 52 academic research grant awards, eight prevention awards, and two product development research awards.
The awards support cancer research and prevention activities taking place in universities and community organizations across Texas. To date, CPRIT has awarded $2.6 billion in grants to Texas research institutions and organizations through its academic research, prevention and product development research programs.
UTSA Main Campus will serve as a designated polling station during the early voting period, today through October 30, and on Election Day, November 3.H-E-B Student Union Ballroom (HSU 1.104)
The Center for Collegiate Recovery presents a discussion series on Recovery. Join the discussion with Dr. Robb Kelly and learn how to build and sustain recovery from addiction. Be prepared to be challenged, encouraged, and enriched!Virtual Event
The tuba and euphonium students of Prof. Gary Poffenbarger will perform remotely in a live-streamed concert to be transmitted via the Department's Facebook page. The students will perform live, from their homes taking turns logging in when they are up and logging off when they are done so the next performer can log in, etc. until the recital is finished.Virtual Event
Are you interested in learning more about how RowdyLink can assist your Student Organization? Are you a new organization leader and want to learn some basics regarding RowdyLink? Please join us at our RowdyLink Lunch and Learn Series. We will be going over various parts of RowdyLink during each series such as Managing your Roster, Mobile Check-In, Managing and Creating Forms, creating events and more.Virtual Event
Chomp and Chat is a series of conversations held casually during lunch on a specific topic. The topic for Oct 28 is cultural appropriation. We will talk the concept in general, but also as it appears during Halloween and Día de los Muertos.Virtual Event
Join Student Health Services as we discuss Spiritual Wellbeing with Counseling and Mental Health Services.Virtual Event
Join us for a drive-thru event from 9 a.m. to noon on Oct. 29 and from 3 p.m. to 6 p.m. on Oct. 30 to give back during this election period. Roadrunners will have the opportunity to give back to the community and get the information needed to make your voice heard for your community. During this experience, you can drive up to make a donation to the Roadrunner Pantry and get all of the voting information you need to early vote this election.Outside Recreation Wellness Center
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UTSA is a proud Hispanic Serving Institution (HSI) as designated by the U.S. Department of Education.
The University of Texas at San Antonio, a Hispanic Serving Institution situated in a global city that has been a crossroads of peoples and cultures for centuries, values diversity and inclusion in all aspects of university life. As an institution expressly founded to advance the education of Mexican Americans and other underserved communities, our university is committed to ending generations of discrimination and inequity. UTSA, a premier public research university, fosters academic excellence through a community of dialogue, discovery and innovation that embraces the uniqueness of each voice.