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Fundamental Concepts, Practical Applications, and Limitations of

Capillary Electrophoresis and Microchip Capillary Electrophoresis
Carlos D. Garcia, Karin Chumbimuni Torres, and Emanuel Carrilho (Eds.) - ISBN: 9780470572177

John Wiley & Sons, Inc.



Latest paper Preface

Capillary electrophoresis (CE) is a powerful tool for analytical separations, but in particular, it excels in the separation of biomolecules. In comparison with traditional analytical techniques, CE offers speed, small sample and solvent consumption, low cost and the possibility of miniaturization. As a consequence, the initial concept describing the separation of proteins in an open tube has evolved into an array of techniques and methodologies that can be competitively applied into the chemical, physical, environmental, clinical, and forensic fields. Based on the most current information and the state of the art related to separations by capillary electrophoresis and microchip capillary electrophoresis, this book aims to provide a critical perspective related not only to the advantages, but also to the limitations of the available techniques. The twenty-one chapters of this book provide information related to fundamental aspects of electrophoretically-driven separations, instrumentation, sampling techniques, separation modes, detection systems, optimization strategies for method development, as well as timely applications. Emphasis was placed in applications in which capillary electrophoresis has objectively demonstrated advantages with respect to other analytical approaches. The book not only provides relevant information to researchers actively working in the field but also represents an instructive platform to introduce the topic in educational settings.



Latest paper Table of Contents

arrow Chapter 1: Critical Evaluation of the Use of Surfactants in Capillary Electrophoresis
Jessica Felhofer, Karin Chumbimuni-Torres, Maria F. Mora, Gabrielle Haby, and Carlos D. García


arrow Chapter 2: Sample Stacking - A Versatile Approach for Analyte Enrichment in CE and Microchip-CE
Bruno Perlattia, Emanuel Carrilho,Fernando Armani Aguiar


arrow Chapter 3: Sampling and Quantitative Analysis in Capillary Electrophoresis
Petr Kubán, Andrus Seiman, Mihkel Kaljurand


arrow Chapter 4: Practical considerations for the design and implementation of High Voltage Power Supplies for Capillary and Microchip Capillary Electrophoresis
Lucas Blanes, Wendell Karlos Tomazelli Coltro, Renata Mayumi Saito, Claudimir Lucio do Lago, Claude Roux and Philip Doble.


arrow Chapter 5: Artificial Neural Networks in Capillary Electrophoresis
Josef Havel, Eladia María Peña-Méndez, Alberto Rojas-Hernández


arrow Chapter 6: Improving the Separation in Microchip Electrophoresis by Surface Modification
M. Teresa Fernández-Abedul, Isabel Álvarez-Martos, Francisco Javier García Alonso, Agustín Costa-García


arrow Chapter 7: Capillary Electrophoretic Reactor and Microchip Capillary Electrophoretic Reactor: Dissociation Kinetic Analysis Method for “Complexes” Using Capillary Electrophoretic Separation Process
Toru Takahashi and Nobuhiko Iki


arrow Chapter 8: Capacitively Coupled Contactless Conductivity Detection (C4D) Applied to Capillary Electrophoresis (CE) and Microchip Electrophoresis (MCE)
José Alberto Fracassi da Silva, Claudimir Lucio do Lago, Dosil Pereira de Jesus, Wendell Karlos Tomazelli Coltro


arrow Chapter 9: Capillary Electrophoresis with Electrochemical Detection
Blánaid White


arrow Chapter 10: Overcoming Challenges in using Microchip Electrophoresis for Extended Monitoring Applications
Scott D. Noblitt and Charles S. Henry


arrow Chapter 11: Distinction of coexisting protein conformations by capillary electrophoresis
Hanno Stutz


arrow Chapter 12: Capillary Electromigration Techniques for the Analysis of Drugs and Metabolites in Biological Matrices: A Critical Appraisal
Cristiane Masetto de Gaitani, Anderson Rodrigo Moraes de Oliveira, and Pierina Sueli Bonato


arrow Chapter 13: Capillary electrophoresis and multi-color fluorescent DNA analysis in an optofluidic chip
Chaitanya Dongre, Hugo J.W.M. Hoekstra, and Markus Pollnau


arrow Chapter 14: Capillary Electrophoresis of Intact Unfractionated Heparin and Related Impurities
Robert Weinberger


arrow Chapter 15: Microchip Capillary Electrophoresis for in situ Planetary Exploration
Peter A. Willis and Amanda M. Stockton


arrow Chapter 16: Rapid Analysis of Charge Heterogeneity of Monoclonal Antibodies by Capillary Zone Electrophoresis and Imaged Capillary Isoelectric Focusing
Yan He, Jim Mo, Xiaoping He and Margaret Ruesch


arrow Chapter 17: Application of capillary electrophoresis for high-throughput screening of drug metabolism
Roman Remínek, Jochen Pauwels, Xu Wang, Jos Hoogmartens, Zdenek Glatz, Ann Van Schepdael


arrow Chapter 18: Electrokinetic Transport of Microparticles in Microfluidic Enclosure Domain
Qian Liang, Chun Yang, and Jianmin Miao


arrow Chapter 19: Integration of nanomaterials in capillary and microchips electrophoresis as a flexible tool
Germán A. Messina, Roberto A. Olsina, Patricia W. Stege


arrow Chapter 20: Microchip Capillary Electrophoresis to Study the Binding of Ligands to Teicoplanin Derivatized on Magnetic Beads
Toni Ann Riveros, Roger Lo, Xiaojun Liu, Marisol Salgado, Hector Carmona and Frank A. Gomez


arrow Chapter 21: Glycomic Profiling through Capillary Electrophoresis and Microchip Capillary Electrophoresis
Yehia Mechref






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