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Faculty
     
  Carlos D. Garcia
Associate Professor

Office Phone: (210) 458-5774
Office: BSE 1.104L
E-Mail: carlos.garcia@utsa.edu

Areas of Specialization
• Capillary Electrophoresis / Microchip capillary Electrophoresis
• Electrochemical Detection
• Interaction of Enzymes with Carbon Nanotubes

Laboratory web page
http://www.utsa.edu/chem/faculty/carlosGarcia/Garcia.html





Research Interests

Microchips are one of the most promising analytical platforms due to the great advantages with respect to conventional bench-top equipment. Microfluidic devices are able to offer custom design, high throughput, sensitivity, selectivity and portability. In order to achieve a real point-of-care measurement device, simple instrumentation has to be integrated to drive the injection and separation. Electrochemical detection (ECD) methods have been widely applied for the detection of bio-compounds because they are less susceptible to decreases in signal magnitude during miniaturization and are already portable and inexpensive. For these reasons, we are very interested in studying the design, operation and biological applications of microchips and capillary electrophoresis. In addition, we are also interested in the rational design of biosensors.






Selected Publications

 

Simultaneous Solid Phase Extraction and Derivatization of Aliphatic Primary Amines Prior to Separation and UV-Absorbance Detection
Jessica L. Felhofer, Karen Scida, Mark Penick, Peter Willis and Carlos D. Garcia
Talanta 115 (2013) 688 - 693.

 

Spectroscopic and Electrochemical Characterization of Nanostructured Optically-Transparent Carbon Electrodes
Tomas E. Benavidez and Carlos D. Garcia
Electrophoresis 34 (2013) 1998 - 2006.

 

Ultra-Thin Optically Transparent Carbon Electrodes Produced from Layers of Adsorbed Proteins
Sarah Alharthi, Tomas E. Benavidez and Carlos D. Garcia
Langmuir 29 (2013) 3320 - 3327.

 

Microfab-less Microfluidic Capillary Electrophoresis Devices
Thiago P. Segato, Samir A. Bhakta, Matthew Gordon, Emanuel Carrilho, Peter A. Willis, Hong Jiao, and Carlos D. Garcia
Analytical Methods 5 (2013) 1652 - 1657.

 

Computational, Electrochemical, and Spectroscopic, Studies of Acetycholinesterase Covalently Attached to Carbon Nanotubes
Murilo F. Cabral, Joseph D. Barrios, Érica M. Kataoka, Sergio A. S. Machado, Emanuel Carrilho, Carlos D. Garcia, and Arturo A. Ayon
Colloids and Surfaces B: Biointerfaces 103 (2013) 624-629.

 

Research Spotlight: The Next Big Thing is Actually Small
Carlos D. Garcia
Bioanalysis 4 (2012) 1717-1722.

 

Unmanned platform for long-range remote analysis of volatile compounds in air samples
E. Tavares da Costa, C. A. Neves, G. M. Hotta, D. T. Rajh Vidal, M. F. Barros, A. A. Ayon, C. D. Garcia, C. L. do Lago
Electrophoresis 33 (2012) 2650-2659.

 

Nanomolar Detection of Glutamate at a Biosensor Based on Screen-Printed Electrodes Modified with Carbon Nanotubes
Raju Khan, Waldemar Gorski and C. D. Garcia
Electroanalysis 23 (2011) 2357 – 2363.

 

Adsorption of Proteins to Thin-Films of PDMS and Its Effect on the Adhesion of Human Endothelial Cells
K. Y. Chumbimuni-Torres, R. E. Coronado, A. M. Mfuh, C. Castro, M. F. Silva, G. R. Negrete, R. Bizios and C. D. Garcia
RSC Advances 4 (2011) 706 - 714

 

Adsorption of Glucose Oxidase to 3-D Scaffolds of Carbon Nanotubes: Analytical Applications
M. Reza Nejadnik, Leonard Francis, and Carlos D. Garcia
Electroanalysis 23 (2011) 1462 – 1469.

 

Nanomolar Detection of Glutamate at a Biosensor Based on Screen-Printed Electrodes Modified with Carbon Nanotubes

Raju Khan, Waldemar Gorski and C. D. Garcia
Electroanalysis 23 (2011)2357 – 2363.

 

 

 

 

Adsorption of Proteins to Thin-Films of PDMS and Its Effect on the Adhesion of Human Endothelial Cells

K. Y. Chumbimuni-Torres, R. E. Coronado, A. M. Mfuh, C. Castro, M. F. Silva, G. R. Negrete, R. Bizios and C. D. Garcia

RSC Advances 4 (2011) 706 - 714


 

 

 

Recent Applications of Carbon-Based Nanomaterials to Analytical Chemistry: A Critical Review
Karen Scida, Patricia W. Stege, Gabrielle Haby, German A. Messina, and Carlos D. Garcia
Analytica Chimica Acta 691 (2011) 6-17.

 

 

 

 

Staining Proteins: A Simple Method to Increase the Sensitivity of Ellipsometric Measurements in Adsorption Studies
M. Reza Nejadnik and Carlos D. Garcia
Colloids and Surfaces B: Biointerfaces 82 (2011) 253–257.


 

 

 

Adsorption Kinetics of Catalase to Thin-Films of Carbon Nanotubes
Jessica Felhofer, Jonathan Caranto, and Carlos D. Garcia
Langmuir 26 (2010) 17178–17183.

 

 

 

Determination of a Setup Correction Function to Obtain Adsorption Kinetic Data at Stagnation Point Flow Conditions
Maria F Mora, Reza Nejadnik, Javier Baylon-Cardiel, Carla E Giacomelli, Carlos D. Garcia
Journal of Colloids and Interface Science 346 (2010) 208 – 215.

 

 

 

 

Electrostatic and Hydrophobic Interactions Involved in CNT Biofunctionalization with Short ss-DNA
Carot, Maria; Torresi, Roberto; Garcia, Carlos; Esplandiu, María José; Giacomelli, Carla
Journal of Physical Chemistry 114 (2010) 4459–4465.

 

 

 

 

Interaction of D-Amino Acid Oxidase with Carbon Nanotubes: Implications in the Design of Biosensors
Maria F. Mora, Carla Giacomelli and Carlos D. Garcia
Analytical Chemistry 81 (2009) 1016 – 1022.

 

 

 

 

Lab-on-a-Robot: Integrated Microchip – Capillary Electrophoresis, Power Supply, Electrochemical Detector, Wireless Unit, and Mobile Platform
C. Berg, D. C. Valdez, P. Bergeron, M. F. Mora, C. D. Garcia and A. Ayon
Electrophoresis 29 (2008) 4914 – 4921.

 

 

 

Electrophoretic Separation of Environmentally Important Phenolic Compounds Using Montmorillonite-Coated Fused Silica
Maria F. Mora and Carlos D. Garcia
Electrophoresis 28 (2007) 1197 – 1203.


 

 

 

 

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