Lydia Martinez Rivera
Sr. Lecturer / Undergraduate Advisor of Record
Office Phone: (210) 458-7051
Office: BSE 1.338
Areas of Specialization
• photochemistry of nucleic acids and proteins
• phototoxicity of xenobiotics
• chemical education
We are interested in studying the mechanisms by which absorption of electromagnetic radiation by topically applied medicinal compounds may lead to the development of erythema, and in the worst case scenario, skin cancer. Our approach begins by studying the basic photophysical properties of these compounds, their photochemical reactions, and reactive intermediates formed in solution, micelles, and cell lines. We are also interested in developing new pedagogies and course material that may help students develop knowledge of basic chemical principles and their relevance to our society.
Photogeneration of fluoride by the fluoroquinolone antimicrobials agents lomefloxacin and fleroxacin.
Martínez, L.J., G. Li and C.F. Chignell.
Photochem. Photobiol. 1997, 65:599-602.
Transient intermediates in the photolysis of ketoprofen in aqueous solutions: unusual photochemistry for the benzophenone chromophore
Martínez, L.J. and J.C. Scaiano
J. Am. Chem. Soc. 1997, 45:11066-11070
Photocleavage of DNA by fluoroquinolone antibacterials.
Martínez, L.J. and C.F. Chignell
J.Photochem. Photobiol. B: Biol. 1998, 45: 51-59
The 254 nm low intensity and 266 nm laser photochemistry of adenosine. Effect of pH and concentration on the reactive precursors of the principal products, adenine and FAPyAde.
Crespo-Hernandez, C.E., L. Martinez, A.E. Gonzalez-Sierra, L. Robles-Irizarry, A. Diaz-Vazquez and R. Arce
J. Photochem. Photobiol. A: Chemistry 2002, 152:123-133.