UTSA COS Summer Research Experience for 2013
Computational Modeling of Ciliary Muscle Dynamics
Accommodation is accomplished by the action of the ciliary muscle. Accommodation is a controlled process in which the feedback loop is closed in the brain at 20-30 Hz; therefore, the dynamic response of the ciliary muscle to brain stimulation is essential in modulating the focus of the eye. Adrian Glasser (Ophthalmology, 1999) has implanted electrodes in the Edinger-Westphal nucleus of monkey brains to enable direct electrical manipulation of the ciliary muscle. Its time-dependent movement was monitored after the onset of stimulus current. We will model the dynamics of this process using image processing to measure changes in the ciliary muscle shape over time and a smooth muscle constitutive model to understand the role of the ciliary muscle in controlling accommodation dynamics.