UTSA COS Summer Research Experience for 2013
Comparative Genomics, Molecular Evolution, and Systems Biology of Gene Families
Approaches range from the use of cutting edge bioinformatic and genomic tools, to statistical modeling and analysis based on evolution and population genetics theory. The lab is particularly interested in (1) the evolutionary mechanisms and systems biology of infectious diseases. The lab is using genomic and related data, coupled with other biochemical and microbiological information, to identify new therapeutic targets and to further study the underlying evolutionary mechanisms in diseases such as malaria; and (2) the molecular evolution of vertebrate gene families, with a particular emphasis on the age distribution and functional divergence of duplicated genes, which are believed to provide the raw material for functional novelty in higher eukaryotes. Of additional interest is the association between sequence evolution and gene network regulation.